Evastin Tablets 10/20 mg
Ezetimibe 10mg · Simvastatin 20mg
Tablet · Prescription medication · Combination
Taeguk Pharmaceutical Co., Ltd.
MFDS item code 201903091 · Approved 2019.05.13
This product's status changed to Expired on 2024.05.13. It may no longer be sold, so consult a doctor or pharmacist before taking it.
Improvement of cholesterol and lipids in hypercholesterolemia (primary, familial) and mixed hyperlipidemia
This medication is used as an adjunct to dietary therapy for lowering high total cholesterol, LDL cholesterol, Apo B protein, and triglycerides in patients with primary hypercholesterolemia, especially heterozygous familial and non-familial, and mixed hyperlipidemia, as well as for increasing HDL cholesterol, the 'good' cholesterol. It can also be given alone to patients with homozygous familial hypercholesterolemia when other lipid-lowering therapies are not effective or cannot be used. This medication is used together with an appropriate diet that includes restrictions on saturated fats and cholesterol, and is prescribed when diet alone or non-drug measures are insufficient. Prior to treatment, secondary causes of hypercholesterolemia, such as diabetes or hypothyroidism, should be evaluated and treated as necessary. Regular monitoring of total cholesterol, LDL, HDL, and triglyceride levels is important to assess treatment progress. This medication helps reduce the risk of atherosclerotic vascular disease due to hypercholesterolemia.
This medication is administered once daily in the evening, regardless of meals. For patients with primary hypercholesterolemia, the dosage range is 10/10 mg to 10/40 mg per day, with the generally recommended starting dose being 10/20 mg per day. Patients with less need for LDL cholesterol reduction may start with 10/10 mg once daily. After initiation of treatment or dose adjustment, blood lipid levels should be checked at intervals of more than 4 weeks.
This medication may cause muscle adverse reactions, so if muscle pain or weakness occurs, it should be reported to a physician immediately. This medication should not be used in patients with poor liver function, liver disease, or in pregnant or nursing women. Additionally, taking this medication with certain other medicines may increase the risk of muscle damage, so it is essential to inform the doctor of any other medications being taken. Elderly patients or those with certain myopathies need to exercise extra caution when using this medication. During treatment, it is advisable to regularly check blood tests to monitor muscle and liver conditions. If there are unexplained muscle pain, tenderness, or weakness while taking this medication, it should be stopped immediately and consult a healthcare professional. This medication should not be used in women who are planning to become pregnant or who may be pregnant, and it should be discontinued immediately upon confirmation of pregnancy. Women who are nursing should also be advised to stop breastfeeding while taking this medication. There is insufficient evidence of safety and efficacy for use in children and adolescents, so it should be used with caution. There is no specific antidote for overdose, but appropriate treatment should be provided based on symptoms.
Hives, angioedema, rash, toxic epidermal necrolysis (Lyell syndrome), erythema multiforme (Stevens-Johnson syndrome), dyspnea, liver abnormalities (jaundice), hepatitis, fulminant hepatic necrosis, severe edema, myasthenia gravis, ophthalmoplegia, myopathy, rhabdomyolysis, severe allergic reactions, severe skin reactions, respiratory problems, sudden and severe headache, altered consciousness, visual disturbances, paralysis, serious neurological symptoms
Headache, diarrhea, influenza, upper respiratory tract infections, muscle pain, limb pain, fatigue, nausea, abdominal pain, constipation, epigastric pain, vomiting, chest pain, chest discomfort, numbness, cough, facial swelling, generalized edema, thirst, fainting, insomnia, gastritis, atrophic gastritis, dyspepsia, mucus stools, irritable bowel syndrome, sore throat, joint pain, low back pain, eyes: cataracts, dermatological and subcutaneous adverse reactions (eczema, itching, rash), alopecia, various
Not everyone experiences these, and they can vary from person to person.
This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, storing the medication at room temperature between 1°C and 30°C will maintain its efficacy.
White to off-white, biconvex, rectangular tablets
30 tablets (10 tablets/PTP × 3)
Even with the same ingredient, strength, dosage form and how it is taken can differ.
Ezetimibe 10mg · Simvastatin 20mg
Tablet · Prescription medication · Combination
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Tablet · Prescription medication · Combination
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Tablet · Prescription medication · Combination
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Tablet · Prescription medication · Combination
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Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
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For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.