Medication info
Olmedica HCT Tablet 10/40/12.5 mg

Olmedica HCT Tablet 10/40/12.5 mg

Prescription medicationTablet경구
Ingredient · strength
Olmesartan Medoxomil›40mg / 1 tabletAmlodipine Besylate›13.888mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
대우제약(주)
Appearance
Round film-coated tablet in reddish-gray
Packaging
30 tablets (10 tablets/Alu-Alu × 3)
Approval status
Active

MFDS item code 201903060 · Approved 2019.05.10 · Insurance code 649605040

Summary

Main use
Improvement in blood pressure control for essential hypertension
Who takes it
Adults · Children
Adult dose
Take one tablet once a day with water, regardless of meals. It is recommended to take it at the same time every day (e.g., morning). The maximum dose is Amlodipine/Olmesartan Medoxomil/Hydrochlorothiazide 10/40/25 mg. Adjust the dosage after an interval of more than 2 weeks considering blood pressure response. Recommended dosage steps: - 5/20/12.5 mg - 5/40/12.5 mg -
Child dose
Safety and efficacy in pediatric patients under 18 years have not been established, and administration of this medication is not recommended.

Ingredients

Manufacturer
대우제약(주)

Efficacy & effects

Improvement in blood pressure control for essential hypertension

  • Essential hypertension
View approved original text

The combination therapy of Amlodipine and Olmesartan Medoxomil is used when blood pressure is not adequately controlled in patients with essential hypertension. These two drugs work through different mechanisms to dilate blood vessels and lower blood pressure. Amlodipine, a calcium channel blocker, relaxes vascular smooth muscle to reduce blood pressure, while Olmesartan Medoxomil, an angiotensin II receptor blocker, prevents vascular constriction and aids in blood pressure control. Proper blood pressure control can reduce the risk of cardiovascular complications. This combination therapy effectively improves hypertension.

How to take

Adult dose

Take one tablet once a day with water, regardless of meals. It is recommended to take it at the same time every day (e.g., morning). The maximum dose is Amlodipine/Olmesartan Medoxomil/Hydrochlorothiazide 10/40/25 mg. Adjust the dosage after an interval of more than 2 weeks considering blood pressure response. Recommended dosage steps: - 5/20/12.5 mg - 5/40/12.5 mg -

Child dose

Safety and efficacy in pediatric patients under 18 years have not been established, and administration of this medication is not recommended.

Precautions

This medication should not be taken during the second and third trimesters of pregnancy as it can cause serious harm to the fetus and newborn. If pregnancy is confirmed, the medication should be discontinued immediately. Individuals allergic to this medication or similar drugs should not use it. Patients with severe hypotension, significant issues with the heart, kidneys, or liver should also avoid this medication. It should be avoided in patients with unstable heart failure or shock after acute myocardial infarction. Patients with reduced blood volume or electrolyte imbalance may experience hypotension, so careful monitoring is required. Patients with impaired kidney function should regularly undergo blood tests to monitor renal function and electrolyte status. This medication is not recommended for patients with compromised liver function or progressive liver disease. Caution should be exercised in patients with specific heart valve diseases or obstructive cardiomyopathy. Due to the blood pressure-lowering effects of this medication, dizziness or drowsiness may occur, so caution should be taken when driving or operating hazardous machinery. This medication may interact with other drugs, so it is essential to inform the doctor or pharmacist of any other medications being taken, especially lithium, non-steroidal anti-inflammatory drugs, or other antihypertensive agents. This medication is not recommended for breastfeeding women, and if breastfeeding is to continue, consultation with a doctor is necessary. It is best not to use this medication in children under 18 years of age as safety and efficacy have not been established. In elderly patients, dosing should start at a low dose considering possible liver and kidney function decline and require careful monitoring. In cases of overdose, severe hypotension and arrhythmias may occur, necessitating immediate medical treatment. This medication should be stored away from direct sunlight and moisture, out of reach of children. Any unusual symptoms such as skin rash, breathing difficulties, or severe swelling during use should prompt immediate medical attention.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), difficulty breathing, jaundice (liver dysfunction), acute renal failure, acute respiratory distress syndrome (ARDS), pulmonary edema, Stevens-Johnson syndrome, thrombosis, embolism, Quincke's edema, myocardial infarction, seizures, severe allergic reactions, severe dermatological reactions, serious neurological symptoms, and severe swelling or urination abnormalities.

Mild side effects

  • Peripheral edema
  • headache
  • dizziness
  • upper respiratory infection
  • nasopharyngitis
  • urinary tract infection
  • sialadenitis
  • leukopenia
  • thrombocytopenia
  • bone marrow suppression
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  • neutropenia/agrannulocytosis
  • hemolytic anemia
  • aplastic anemia
  • drug hypersensitivity
  • hyperkalemia
  • hypokalemia
  • loss of appetite
  • diabetes
  • hypercalcemia
  • hyperglycemia
  • hypomagnesemia
  • hyponatremia
  • hypochloremia
  • hypertriglyceridemia
  • hypercholesterolemia
  • hyperuricemia
  • and hypochloremic metabolic alkalosis.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. Additionally, it is best to store it at room temperature between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

Round film-coated tablet in reddish-gray

Package unit

30 tablets (10 tablets/Alu-Alu × 3)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.