Medication info
Cerecob Capsule 200 mg (Celecoxib)

Cerecob Capsule 200 mg (Celecoxib)

Prescription medicationHard capsule
Ingredient · strength
Celecoxib›200mg / 1 capsule
Manufacturer / importer
You & Life Sciences Co., Ltd.
Appearance
A capsule filled with white to pale yellow powder, with a white shell on the top and bottom.
Packaging
30 capsules/bottle, 100 capsules/bottle
Approval status
Active

MFDS item code 201903005 · Approved 2019.05.09 · Insurance code 058800080

Summary

Main use
Relief of arthritis, spondylitis, acute pain in adults, and primary dysmenorrhea
Who uses it
Adults
Adult dosage
The minimum recommended dose of this medicine should be adjusted for each patient, and it may be administered with or without food. Adults: Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg per dose in 2 divided doses daily. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib per dose twice daily. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg per dose in 2 divided doses daily. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks of taking 400 mg daily, other treatment options should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

Ingredients

Manufacturer
You & Life Sciences Co., Ltd.

Efficacy & effects

Relief of arthritis, spondylitis, acute pain in adults, and primary dysmenorrhea

  • Symptoms of osteoarthritis
  • degenerative arthritis
  • rheumatoid arthritis
  • ankylosing spondylitis
  • acute pain
  • primary dysmenorrhea
View approved original text

This medication is used to relieve pain and inflammation symptoms caused by arthritis, such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It also reduces acute pain that occurs after surgery or tooth extraction and is effective for primary dysmenorrhea. In other words, this drug helps improve various pain and inflammation symptoms.

Dosage and Administration

Adult dosage

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be administered with or without food. Adults: Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg per dose in 2 divided doses daily. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib per dose twice daily. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg per dose in 2 divided doses daily. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks of taking 400 mg daily, other treatment options should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

Precautions

This medication may cause gastric bleeding if taken by individuals who consume large amounts of alcohol daily; therefore, it is essential to consult a physician or pharmacist. This drug can increase the risk of heart or cerebrovascular problems; hence, it should only be used at the minimum effective dose for the shortest duration possible. If symptoms such as chest pain, shortness of breath, weakness, or slurred speech occur while taking this medication, immediate medical attention should be sought. This drug can cause ulcers or bleeding in the stomach, and particular care should be taken by those of advanced age or with a history of gastrointestinal disorders. If symptoms such as epigastric pain, indigestion, black stools, or hematemesis appear, it is critical to visit a hospital immediately. Individuals with allergic reactions, specific liver, kidney, or heart diseases, as well as pregnant or nursing women, should not take this medication. Those with weakened liver or kidney function, or a history of asthma, hypertension, heart failure, or diabetes should use this drug cautiously and consult their doctor. Regular checks of liver and kidney function should be conducted during treatment, and any abnormal signs must be reported immediately. This medication may cause side effects such as headaches, dizziness, indigestion, vomiting, skin rashes, edema, hypertension, etc.; symptoms should be carefully monitored. This medication may interact with other drugs, so it is crucial to inform your doctor or pharmacist of any currently taken medications. Pregnant women or those planning to become pregnant should not take this medication, and if pregnancy is confirmed during treatment, it should be discontinued immediately. Dizziness or drowsiness may occur while taking this medication, so driving or operating machinery is not recommended. Children and adolescents should not use this medication as its safety and efficacy have not been established. The elderly may have decreased liver, kidney, and heart function, so special attention is required when taking this medication. This drug should be kept out of reach of children and should not be transferred to any other container.

Side effects

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial swelling, influenza-like illness, damage, taste disorder, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, kidney dysfunction, acute renal failure, interstitial nephritis, headache, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, angioedema, insomnia, loss of appetite, increased appetite, depression, irritability, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasms, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urine urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, synovial cyst, arthralgia, osteoarthritis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various parts, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathies, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reactions, skin nodules, blurred vision, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, phototoxic reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular-interstitial nephritis, nephrotic syndrome, membranous nephropathy, menstrual disorders, female infertility, chest pain, lethargy, drowsiness, nausea, vomiting, upper abdominal pain, gastrointestinal bleeding, hypertension, acute renal failure, respiratory depression, coma

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air from entering, and it is important to maintain the storage temperature between 15 to 30 degrees Celsius. This will help ensure the medication's effectiveness.

Appearance and packaging

Appearance

A capsule filled with white to pale yellow powder, with a white shell on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.