AceNale CR Tablets (Aceclofenac)

Adult dose

As aceclofenac, take 200 mg once daily. Do not chew or crush the tablets; take them whole. To minimize cardiovascular adverse reactions, it should be administered at the lowest effective dose for the shortest duration.

This medication may increase the risk of gastrointestinal bleeding in individuals who regularly consume more than three drinks of alcohol daily, so consultation with a doctor or pharmacist is mandatory. This medication may increase the risk of cardiovascular and cerebrovascular events; therefore, patients with risk factors for cardiovascular diseases such as heart failure, hypertension, and diabetes should use it cautiously. As the longer the dosage and duration increase, the greater the risk to the cardiovascular system could become, it should be taken at the lowest effective dose for the shortest duration possible, and treatment responses and symptoms should be monitored continuously. Older adults or patients with a history of gastrointestinal diseases are at a higher risk of serious gastrointestinal conditions such as bleeding, ulcers, and perforations, and should be particularly careful; immediate medical attention is required if symptoms appear. It should not be taken if there is active peptic ulcer or bleeding or if there is an allergy to this drug or similar medications. Patients with a history of asthma or allergic reactions may experience severe reactions while taking this medication, so it should be avoided or used with caution. Pregnant women in late pregnancy and breastfeeding mothers should not take this medication, and careful administration at the lowest effective dose is required only if absolutely necessary during early or mid-pregnancy. This drug may affect liver and kidney function, so patients with liver or kidney impairment should take it under medical supervision. Central nervous system side effects such as dizziness or drowsiness may occur, so driving or operating hazardous machinery is not advisable. This drug may interact with several other medications; therefore, if you are taking other drugs, you must consult a doctor, especially when taking anticoagulants, diuretics, or blood pressure medications. Regular blood tests and liver and kidney function tests are needed to check for abnormalities during long-term use. If skin rashes, itching, difficulty breathing, or other abnormal reactions occur, stop taking the medication immediately and consult a healthcare professional. The safety and efficacy of this medication in children and teenagers have not been established and are therefore not recommended for use. Elderly patients are at a higher risk of gastrointestinal bleeding and perforation, so special care is needed during administration. In cases of overdose, symptoms such as gastrointestinal irritation, hypotension, respiratory depression, and seizures may occur; immediate medical attention should be sought for appropriate treatment. This medication should be kept out of reach of children, and care should be taken as transferring it to another container may compromise quality.

Serious side effects

Hives, severe swelling (edema), severe allergic reactions, shock, anaphylaxis, severe rash with high fever, blisters, shedding skin, oral/eye mucosal pain, severe skin adverse reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, difficulty in breathing, bronchospasm, wheezing, yellowing of skin or eyes (jaundice), feelings of extreme fatigue, liver abnormalities (jaundice), sudden and

Mild side effects

• Dizziness
• abnormal liver enzyme levels
• itching
• rash
• anemia
• leukopenia
• thrombocytopenia
• neutropenia
• hemolytic anemia
• aplastic anemia

This medication should be stored in a tightly closed container to avoid exposure to air and moisture. It is best to maintain a storage temperature between 1°C and 30°C. This helps to preserve the effectiveness of the drug for a longer period.

Appearance

White rectangular sustained-release film-coated tablets

Package unit

100 tablets/bottle, 30 tablets/bottle