Pariaton Tablet 20 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: administer 10 mg orally once daily; may increase to 20 mg once daily depending on symptoms. For erosive or ulcerative gastroesophageal reflux disease: administer 10 mg or 20 mg once daily for 4 to 8 weeks. If not resolved after 8 weeks of proton pump inhibitor (PPI) treatment, an additional 8-week course of 10 mg or 20 mg may be taken orally twice daily.

This medication should not be used in patients who have allergic reactions to specific components or the drug itself, or who have had such reactions in the past. Caution is required when combined with penicillin or macrolide antibiotics, especially during Helicobacter pylori eradication therapy. It is safer for pregnant or nursing women to avoid taking this medication. Patients with impaired liver function or the elderly should use it cautiously as adverse reactions may occur. This medication contains a dye, Yellow No. 4, so caution is needed for those allergic to this component. If signs of hypersensitivity such as rash or itching occur during use, discontinue the medication immediately. Changes in red blood cell or white blood cell counts may occur in blood tests, so regular monitoring is recommended. Regular liver function tests should also be conducted, and if abnormalities are found, the medication should be discontinued. Caution is advised as heart-related symptoms or abnormal blood pressure, headaches, and dizziness may occur. Gastrointestinal symptoms such as diarrhea, abdominal pain, nausea may occur, and severe cases may require a visit to the hospital. Neuropsychiatric symptoms such as headache, insomnia, anxiety, and drowsiness may occur, so caution is needed when driving or operating machinery. Respiratory symptoms such as cough or difficulty breathing may happen, so consult a doctor immediately if abnormalities arise. Musculoskeletal symptoms such as muscle pain or joint pain have also been reported. Skin rashes, hair loss, and in severe cases, serious skin reactions like Stevens-Johnson syndrome may occur. Visual abnormalities such as blurred vision or tinnitus can occur, so monitoring is necessary if any such symptoms arise. Urinary issues may also occur, so inform your physician if there are difficulties in urination or hematuria. Long-term use may increase the risk of fractures, so caution is needed. This drug has interactions with some medications, so always consult a medical expert when taking it with other drugs. Particularly, the risk of bleeding may increase when combined with medications affecting blood coagulation. The safety in pregnant or nursing women is not established, so it is advisable to refrain from use. If abnormal symptoms occur during use, inform healthcare personnel immediately and seek treatment. This medication should not be chewed or crushed and must be swallowed whole in tablet form. Keep out of reach of children, and it is advisable not to transfer it to other containers. Regular checks of blood tests, liver function tests, and magnesium levels are necessary during long-term use. Caution is advised as drowsiness may occur when driving or operating machinery.

Serious side effects

Urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, changes in urine output.

Mild side effects

• Rash
• itching
• decrease in red blood cells
• decrease in white blood cells
• increase in white blood cells
• increase in eosinophils
• increase in neutrophils
• decrease in lymphocytes
• anemia
• petechiae

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. Additionally, avoid storing it in excessively hot or cold places, and it is recommended to keep it at room temperature between 1 and 30 degrees Celsius.

Appearance

Pale yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets/PTP x 2)