Ezetimibe 10 mg Tablets (Ezetimibe)

Adult dosage

The recommended dose of this medication is 10 mg once daily, taken regardless of meals. When co-administered with HMG-CoA reductase inhibitors, it should be started at the recommended initial dose of HMG-CoA reductase inhibitors alongside this medication. If a high dose of HMG-CoA reductase inhibitors is already being administered, this medication can be combined without changing the dose of HMG-CoA reductase inhibitors.

This medication should not be used in patients allergic to specific ingredients. Patients with active liver disease or persistently elevated liver enzyme levels of unknown cause should not combine this medication with statins. It is safe for pregnant or nursing women not to take this medication in conjunction with statins or fenofibrate. Patients with severe liver dysfunction or gallbladder disease or severe kidney dysfunction should not take this medication with fenofibrate. This medication contains lactose, so it should not be taken by patients with lactose intolerance or certain genetic metabolic disorders. Patients with moderate to severe liver dysfunction may have increased exposure to this medication, so its use is not recommended. Generally, this medication is safe, but side effects such as headache, abdominal pain, diarrhea, fatigue, and muscle pain may occur, so caution is advised. If used in conjunction with statins, there is a possibility of elevated liver enzymes, so liver function tests should be performed regularly. If symptoms of muscle pain or weakness appear, inform a doctor immediately and discontinue use. Patients with severe kidney impairment may take this medication without dose adjustment, but those with decreased kidney function should be closely monitored according to a doctor's instructions. This medication may interact with other drugs, so caution is necessary when taken with cholestyramine, fibrates, cyclosporine, anticoagulants, etc. Women who are pregnant or of childbearing potential should consult a doctor before using this medication, and breastfeeding should also be avoided. Children under 6 years of age are recommended not to take this medication, while children and adolescents over 6 years should use it under medical guidance. Older adults can also take it, but some may be more sensitive to the medication, so caution is needed. In cases of overdose, there is no specific antidote, so appropriate treatment should be obtained based on symptoms, and it should be kept out of reach of children.

Serious side effects

Hives, angioedema, anaphylaxis, hepatitis, thrombocytopenia, pancreatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), erythema multiforme, severe skin reactions (SCARs), drug-induced liver injury, renal failure, severe edema, hypersensitivity

Mild side effects

• Fatigue
• abdominal pain
• diarrhea
• viral infections
• pharyngitis
• sinusitis
• joint pain
• low back pain
• cough
• chest pain

This medication is sensitive to air and moisture, so it should be stored in a sealed container. Additionally, it is best to store the medication at room temperature between 1 degree and 30 degrees Celsius, away from extremes of heat or cold.

Appearance

White to almost white rectangular tablets

Package unit

30 tablets (10 tablets/PTP x 3)