Ezetimibe Tablet (Ezetimibe)

Adult dosage

The recommended dosage of this medication is 10 mg once daily, administered without regard to meals. When used in combination with HMG-CoA reductase inhibitors, treatment should begin at the recommended starting dose of HMG-CoA reductase inhibitors in conjunction with this medication, and if the patient is already receiving a high dose of HMG-CoA reductase inhibitors, this medication should be used concurrently while maintaining the dosage of HMG-CoA reductase inhibitors.

This medication should not be used in patients with allergies to specific components. Patients with severely impaired liver function or persistently elevated liver enzyme levels without a known cause should not take this medication in conjunction with other drugs that may affect liver function. The use of this medication is prohibited in pregnant or breastfeeding women in conjunction with certain lipid-lowering agents, and women of childbearing age should consult a physician before use. Patients with lactose intolerance or specific genetic metabolic disorders should not take this medication. Patients with moderate to severe liver impairment should use caution as the effects of this medication may be exaggerated. Clinical trial results indicate that this medication can generally be used safely; however, side effects such as headache, abdominal pain, diarrhea, and fatigue may occur. When this medication is combined with other lipid-lowering agents, regular liver function testing is necessary due to the possibility of elevated liver enzyme levels. If symptoms such as myalgia or muscle weakness occur, patients should immediately inform their physician and discontinue medication if necessary. Patients with severely impaired kidney function can take this medication, but dosage adjustments or special care may be needed in some cases. This medication can interact with other drugs, so it is important to consult a physician when taking it with anticoagulants, immunosuppressants, or lipid-lowering agents. Use during pregnancy may pose a risk to the fetus, so pregnant women should use it cautiously under a doctor's guidance. Breastfeeding women should avoid this medication as it may be excreted in breast milk. It is not recommended for children under 6 years old, and children or adolescents over 6 years old should be administered under a doctor's guidance. It can also be safely used in elderly patients, although some elderly individuals may be more sensitive to the medication, thus caution is advised. In case of overdose, there is no specific antidote; treatment based on symptoms is important. This medication should be stored out of reach of children, and it is safer not to transfer it to another container.

Serious side effects

Hives, severe swelling (edema), anaphylaxis, angioedema, rash, erythema multiforme, hepatitis, thrombocytopenia, pancreatitis, cholelithiasis, cholecystitis, gallbladder-related adverse reactions, liver dysfunction, kidney failure (nephropathy), myopathy, rhabdomyolysis, persistent elevation of aminotransferase levels, increase in creatine phosphokinase levels, severe liver enzyme abnormalities, serious liver abnormalities, severe muscle abnormalities, severe edema or urinary abnormalities

Mild side effects

• Headache
• abdominal pain
• diarrhea
• fatigue
• constipation
• flatulence
• nausea
• myalgia
• dizziness
• sensory disturbance

This medication is sensitive to air and moisture, so it should be stored in a sealed container. It is recommended to keep it at room temperature between 1 degree and 30 degrees Celsius. This helps maintain the medication's effectiveness and safety.

Appearance

White to nearly white rectangular tablets

Package unit

30 tablets (10 tablets/PTP×3)