Celecoxib Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be taken with or without food. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of taking 400 mg daily, another treatment should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should not be taken by individuals who regularly consume alcohol in significant amounts, as it may increase the risk of gastrointestinal bleeding; consultation with a doctor or pharmacist is imperative. It may raise the risk of cardiovascular diseases, possibly leading to serious issues such as myocardial infarction or stroke, hence should be used at minimal doses and for short durations only. There is a risk of gastrointestinal perforation, ulcers, and bleeding, so caution is advised particularly for elderly patients or those with a history of gastrointestinal issues. This medication should not be administered to individuals with certain allergy histories, severe liver and kidney disorders, or active gastrointestinal bleeding. Patients with liver or kidney impairment, asthma, heart failure, and hypertension should consult with a doctor before taking this medication. Various side effects may occur such as dyspepsia, headache, dizziness, hypertension, edema, skin rash, and it is essential to inform medical personnel immediately about any abnormal symptoms. Since this drug is metabolized in the liver, it may interact with other medications; therefore, consultation with a doctor or pharmacist is recommended if other medications are being taken. It is safer for pregnant women or those who may become pregnant, as well as nursing mothers, to avoid this medication, and caution is needed for those planning pregnancy. Elderly individuals may have reduced kidney and liver function, requiring careful observation when taking this medication. Regular blood tests and liver and kidney function tests are necessary during prolonged use, and discontinuation may be required if abnormal findings are present. Caution should be exercised when driving or operating machinery due to possible dizziness or drowsiness. In cases of overdose, symptoms such as vomiting, lethargy, and gastrointestinal bleeding may occur, and immediate medical attention should be sought. Store this medication in a place out of reach of children, and do not transfer it to another container.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial swelling, influenza-like illness, damage, headache, leg cramps, sensory impairment, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergic exacerbation, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, angioedema, loss of appetite, increased appetite, depression, neural hyperreactivity, drowsiness, fatal intracranial hemorrhage, hallucinations, worsening of epilepsy, upper respiratory infections, bronchospasm, exacerbated bronchospasm, shortness of breath, laryngitis, pneumonia, nosebleed, voice disorders, vesicular dermatitis, dermatitis, nail diseases, photosensitivity reactions, pruritus, erythematous rashes, maculopapular rashes, skin diseases, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, skin and mucosal syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash, arrhythmia, left ventricular hypertrophy, angina pectoris, unstable angina, coronary artery disease, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, sinus bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebral vascular accident, peripheral gangrene, thrombophlebitis, vasculitis, deep vein thrombosis, intracerebral hemorrhage, cellulitis, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, chest neoplasms, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, sensorineural hearing loss, liver function abnormalities, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, elevated BUN, elevated CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, elevated LDH, hypoglycemia, hyponatremia, joint sacs, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fractures, tendon rupture, back pain, muscle stiffness, decreased hematocrit, increased hemoglobin, petechial hemorrhage, nosebleed, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, folliculitis, contact dermatitis, injection site reactions, skin nodules, gustatory dysfunction, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual confusion, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reactions, vasculitis, interstitial pneumonia, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease.

This medication should be stored in a tightly sealed container to prevent air exposure, ideally at a temperature between 15 to 30 degrees Celsius. This helps maintain the drug's effectiveness and prevents deterioration.

Appearance

This is a white capsule filled with a white to pale yellow powder, with blue stripes on the top and bottom.

Package unit

30 capsules / bottle, 100 capsules / bottle