Exome Tablet 20 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with water or another liquid and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD): - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If esophagitis is untreated or symptoms persist, an additional 4 weeks of treatment is necessary. - Maintenance therapy to prevent recurrence of esophagitis: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 1

Children's dosage

Adolescents over 12 years: - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If treatment is ineffective or symptoms persist, an additional 4 weeks of treatment is required. - Treatment of gastroesophageal reflux disease without esophagitis.

This medicine should not be administered to patients with a known allergy to specific ingredients or benzamidazoles or those who have experienced hypersensitivity reactions. Additionally, patients taking certain antibiotics or antiviral agents used in conjunction with this drug for the eradication of Helicobacter pylori should not be treated with this medication. It is also safest not to administer this drug to breastfeeding women or patients with a history of myocardial infarction. This medication contains the dye Erythrosine (Red 3), so patients allergic to this substance should use it with caution. Various side effects may occur during use, including headache, abdominal pain, diarrhea, skin rashes, muscle pain, and hypomagnesemia. Especially with long-term use, regular blood tests or magnesium level checks should be conducted, and if abnormal symptoms appear, consult a doctor immediately. This medication reduces gastric acid secretion, which can increase bacterial growth in the stomach and raise the risk of infection; therefore, notify healthcare personnel if diarrhea persists. Moreover, long-term high-dose use may increase the risk of fractures, so osteoporosis patients need to be cautious. This medication can interact with many other drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist before use. During pregnancy, the safety of this medication is not fully established, so pregnant women should use it cautiously, and it is advisable to avoid taking it while breastfeeding. In cases of overdose, there is no specific antidote, so symptomatic treatment should be provided while monitoring closely. Store out of reach of children and do not transfer to another container.

Serious side effects

Urticaria, severe swelling (angioedema), anaphylactic reaction/shock, severe rash with high fever, blistering, skin peeling, pain in oral/ocular mucosa, mucosal membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), dyspnea or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough + fever.

Mild side effects

• Headache
• dizziness
• paresthesia
• drowsiness
• taste disturbances
• blurred vision
• vertigo
• bronchospasm
• abdominal pain
• constipation

This medication should be stored in a tightly closed container to protect it from air and moisture, and the storage temperature should be maintained between 1 to 30 degrees Celsius (room temperature). By storing it this way, the effectiveness of the drug can be maintained for a long time.

Appearance

Pale pink, rectangular film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu*2)