Metritat Tablet 15/850 mg

Adult dosage

The dosage of this medication should be individualized based on the efficacy and tolerability within the maximum doses of each ingredient which are pioglitazone 30 mg and metformin 2500 mg. The initial dose should be based on the patient's current treatment regimen, starting with one tablet of this medication daily for patients on metformin or pioglitazone monotherapy based on their current dosing. Switching from pioglitazone and metformin combination therapy

This medication is an antidiabetic drug that helps control blood sugar levels. However, it should not be used in patients with poor kidney function or severe heart failure. Rarely, this medication can cause a serious side effect called lactic acidosis, which is an excessive accumulation of lactic acid in the body leading to a dangerous condition. Lactic acidosis may present with symptoms such as vomiting, abdominal pain, muscle pain, shortness of breath, and weakness, and if these symptoms appear, the doctor should be notified immediately. Patients with poor liver function should also avoid using this medication, and excessive alcohol consumption should be avoided. In addition, it may put a strain on the heart, so special caution is needed if there are symptoms of heart failure or heart disease. While taking this medication, regular kidney and liver function tests should be conducted, and blood sugar levels should be consistently monitored. Pregnant or breastfeeding women should not use this medication. Safety and efficacy have not been established in children, so it should not be administered to them. If symptoms of heart failure such as sudden weight gain, swelling, or shortness of breath occur during treatment, a doctor should be consulted immediately. Additionally, there may be interactions when taken with other medications, so it is essential to discuss all current medications with a doctor or pharmacist. When undergoing surgery or imaging tests, this medication should be temporarily discontinued based on the doctor's instructions. In case of overdose, consult a medical institution immediately for appropriate treatment.

Serious side effects

Severe lactic acidosis, hypoglycemia, congestive heart failure, severe heart failure, worsening heart failure, acute kidney function deterioration, liver failure, bladder cancer, jaundice, severe liver dysfunction, acute coronary syndrome, acute myocardial infarction, kidney failure, acute renal failure, lactic acidosis, acute acidosis, severe neurological symptoms, severe edema accompanied by elevated blood pressure, cardiac hypertrophy, severe liver damage, fatal liver failure, severe allergic reactions

Mild side effects

• Upper respiratory infection
• diarrhea
• nausea
• headache
• urinary tract infection
• sinusitis
• dizziness
• lower limb edema
• weight gain
• anemia

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is best to keep it at room temperature between 1 to 30 degrees Celsius.

Appearance

White to grayish-white oblong film-coated tablet

Package unit

30 tablets (10 tablets/PTP*3)