Piros Tablet 30 mg (Pioglitazone Hydrochloride)

Adult dosage

This medication is taken orally once daily regardless of meals. For monotherapy, begin with 15 mg once daily, and if response is insufficient, the dose can be increased to 30 mg once daily. For combination therapy, continue with 15 mg once daily, with a maximum recommended dose not to exceed 30 mg once daily.

Children's dosage

There is no experience with the use of this medication in children under 18 years of age, hence use is not recommended.

This medication is used to treat type 2 diabetes and acts to improve insulin resistance. Some patients taking this medication may experience heart-related issues, so if symptoms of heart failure such as sudden weight gain, shortness of breath, or leg swelling occur, they should seek medical attention immediately. This medication should not be taken by patients with heart failure or a history of heart failure. Additionally, this medication can cause fluid retention, which may worsen heart failure; therefore, caution is needed when prescribed to patients with cardiovascular conditions. Patients taking this medication should inform their doctor immediately if they experience symptoms such as hematuria, urinary difficulties, or urgency, as these may indicate a potential risk for bladder cancer. This medication is not administered to patients with impaired liver function, severe kidney disease, or active bladder cancer, or those with a history of bladder cancer. Women who are pregnant or may become pregnant should not take this medication, and premenopausal women should use effective contraception as this medication may stimulate ovulation and increase the risk of pregnancy. When taken with other hypoglycemic agents or insulin, there may be an increased risk of hypoglycemia; therefore, patients should be well-informed about hypoglycemic symptoms and dose adjustments of other medications may be necessary. Regular liver function tests and blood glucose monitoring are recommended while taking this medication, and if symptoms such as sudden weight gain, swelling, or shortness of breath occur, immediate consultation with healthcare professionals is needed. Common side effects of this medication may include edema, weight gain, headache, and upper respiratory infections, and there may be an increased risk of fractures, especially in women, so attention to bone health is necessary. Overdosage may not present with specific symptoms, but appropriate treatment should be given depending on the symptoms. The safety and efficacy of this medication in children have not been established, and caution is warranted in the elderly as well. There may be drug interactions, so any concurrent medications should be discussed with a doctor or pharmacist. Store this medication in its original container, out of reach of children.

Serious side effects

Congestive heart failure, worsening heart failure, myocardial infarction, stroke, severe edema, and fluid retention requiring hospitalization, hypoglycemia leading to hospitalization, liver abnormalities (including signs of jaundice), severe allergic reactions (urticaria), severe skin adverse reactions (serious rash, blisters, skin sloughing), serious neurological symptoms (headache, seizures, consciousness disruption, visual disturbances, paralysis), bladder cancer (active or with history), hospitalization due to heart failure, liver failure

Mild side effects

• Upper respiratory infection
• headache
• sinusitis
• myalgia
• pharyngitis
• abdominal bloating
• weight gain
• hypoglycemia
• urinary tract infection
• back pain

This medication should be stored in a container that blocks light and air, and care should be taken to avoid moisture. The recommended storage temperature is between 15°C and 30°C, preferably around 25°C in a cool place.

Appearance

White round tablet

Package unit

30 tablets/bottle, 100 tablets/bottle