Levodipine 5 mg (Esamlodipine Besilate Hydrate)

Adult dose

This medication should be taken with a sufficient amount of water. Esamlodipine is administered orally once a day at a dose of 2.5 mg, and may be increased to a maximum of 5 mg per day depending on the patient's response. Adjustments should be made appropriately based on symptoms.

This medication should not be administered to certain patients. Patients allergic to this drug or its components, or to similar types of medications, should not use it. Pregnant women or women who may become pregnant, as well as nursing mothers, should not take this medication. Patients experiencing severe heart function impairment, shock, serious heart valve problems, unstable angina, or those recently experiencing a myocardial infarction should also avoid using this drug. It is safer for patients with severely impaired liver function and very low blood pressure to refrain from taking this medication. Additionally, since this drug contains lactose, patients with genetic disorders that prevent lactose digestion should not take it. Caution is advised when using this drug in patients with severely impaired kidney function, particularly those on dialysis, elderly patients, patients with acute heart failure, those with very high blood pressure, and patients with moderately impaired liver function. Various side effects may occur when taking this medication. The most common side effects include facial flushing with warmth, fatigue, swelling, palpitations, dizziness and headaches, abdominal pain, nausea, and drowsiness. Rarely, dry mouth or excessive sweating, excessively low blood pressure, itching, rash, hair loss, mood changes, insomnia, cough, and difficulty breathing may occur; consult a doctor if abnormal symptoms arise. This medication should not be abruptly discontinued as symptoms may worsen. It should be tapered off gradually at the direction of a physician. Patients with impaired liver function may experience prolonged effects from this drug, necessitating careful monitoring. This medication should be taken with sufficient water, as a drop in blood pressure may cause dizziness; caution is needed when driving or operating hazardous machinery. This drug can interact with other medications, so it is essential to inform a doctor or pharmacist if other medications are being taken. Particularly, it is advisable to avoid taking it with grapefruit juice, as it may enhance the effects of this drug. It is safest for pregnant or nursing women not to use this drug, and nursing should be discontinued while using it. This medication is only suitable for children aged 6 years and older, and safety and efficacy have not been established for children under 6. Elderly patients may have higher concentrations of the drug in their bodies for longer periods, so they should start with a lower dose and use it cautiously. In cases of overdose, excessively low blood pressure and cardiac issues may arise, necessitating immediate medical attention, and detoxification treatment may be required if necessary. Lastly, this medication should be kept out of reach of children, and it is advisable not to transfer it to another container.

Serious side effects

• Hives
• angioedema
• toxic epidermal necrolysis
• jaundice
• sudden and severe headache
• paralysis

Mild side effects

• Facial flushing with warmth
• fatigue
• swelling
• palpitations
• dizziness
• headaches
• migraines
• weakness
• abdominal pain
• nausea

This medication may be sensitive to air or moisture; therefore, it must be stored in a tightly closed container. It is recommended to maintain storage temperatures between 1 degree and 30 degrees Celsius at room temperature. Proper storage will help maintain the medication's effectiveness for a longer time.

Appearance

White octagonal tablets

Package unit

30 tablets/bottle