Pitamint Metreong 15/850 mg

Adult dosage

This medication is typically taken with meals when divided throughout the day, which can help to reduce gastrointestinal adverse effects related to metformin. Start with 1 tablet per day and gradually adjust the dosage based on the adequacy of the therapeutic response. The dosage should be individualized based on efficacy and tolerability within a maximum range of 30 mg of pioglitazone and 2500 mg of metformin. Patients with renal impairment, elderly patients, and frail patients

This medication is comprised of two main components, each of which aids in blood sugar control, but there are important considerations to keep in mind when taking it. First, one component of this medication can cause a serious side effect known as lactic acidosis in patients with impaired kidney function or liver dysfunction. Lactic acidosis is a condition in which lactate accumulates excessively in the bloodstream, causing harm to the body, and while rare, it can be fatal; therefore, regular monitoring of kidney or liver health is essential. Second, this medication can place additional strain on the heart and should not be administered to patients with heart failure or severe heart disease. If symptoms of heart failure arise, medical consultation should be sought immediately, and careful observation of symptoms such as weight gain or edema is necessary. Third, it is advisable not to use this medication in patients with a history of bladder cancer or active bladder cancer. If symptoms such as hematuria or urinary difficulties occur, medical staff should be informed immediately. Fourth, excessive alcohol consumption should be avoided while taking this medication, and temporary discontinuation may be necessary before and after surgery or in cases of acute infections or dehydration. Fifth, although this medication lowers blood sugar levels, caution is warranted as the risk of hypoglycemia may increase when taken with other blood glucose-lowering agents. Sixth, in elderly patients, renal function may decline, thus necessitating dose adjustments and regular monitoring of kidney function. Lastly, women who are pregnant or breastfeeding should not take this medication, and its safety and efficacy in pediatric patients have not been established. Therefore, regular blood tests and observation of symptoms are crucial while taking this medication, and immediate consultation with healthcare professionals should be undertaken if any abnormalities arise.

Serious side effects

Heart failure, lactic acidosis, hypoglycemia, liver failure, jaundice, bladder cancer, severe allergic reactions, severe edema, increased blood pressure, severe neurological symptoms (headache, seizures, altered consciousness, visual disturbances, paralysis), difficulty breathing, asthma attacks, acute deterioration of renal function, sepsis, liver dysfunction, acute myocardial infarction, cardiopulmonary disease, worsening heart failure, worsening heart disease, pulmonary infarction, severe respiratory dysfunction, hypoxia, following acute alcohol poisoning

Mild side effects

• Upper respiratory infection
• diarrhea
• nausea
• headache
• urinary tract infection
• sinusitis
• dizziness
• lower limb edema
• weight gain
• dyspepsia

This medication should be stored in a tightly sealed container to protect it from air and moisture, and the storage temperature should be maintained at room temperature between 1 to 30 degrees Celsius. By storing it this way, the effectiveness of the medication can be preserved for a longer period.

Appearance

White to grayish-white, oblong film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP*3)]