Ezirol Tablet (Ezetimibe)

Adult dosage

The recommended dose of this medication is 10 mg once daily, taken regardless of meals. When administered in combination with HMG-CoA reductase inhibitors, for patients with primary hypercholesterolemia, treatment should be initiated with this drug at the recommended initial dose of the HMG-CoA reductase inhibitor, and if the patient is already on a high dose of the HMG-CoA reductase inhibitor, the dose of the HMG-CoA reductase inhibitor should be maintained while starting this medication.

This medication should not be used by patients with allergies to specific ingredients. Patients with active liver disease or persistent liver dysfunction should not take this medication along with other specific lipid-lowering agents. Women who are pregnant or breastfeeding should use caution as concomitant use with certain lipid-lowering drugs is prohibited. This drug is not recommended for patients with moderate to severe liver impairment and should be used with caution in such cases. While taking this medication, symptoms such as headache, abdominal pain, diarrhea, fatigue, and myalgia may occur, and if unusual symptoms arise, consultation with a physician is advised. If symptoms such as myalgia or muscle weakness occur, medical professionals should be notified immediately, and medication may be discontinued if necessary. Patients with severe renal impairment do not require dosage adjustment for this drug, but it is important to periodically check renal function status. There may be interactions with other medications, so it is important to inform the physician if taking cholestyramine, fibrates, cyclosporine, anticoagulants, etc. Pregnant or breastfeeding women should carefully consider the potential risks and benefits of using this medication and avoid use if possible. This medication is not recommended for children under 6 years of age and should be administered to children and adolescents aged 6 years and over under the direction of a physician. Elderly patients can also use this drug, but careful observation should be exercised considering age-related sensitivity differences. When storing the medication, it should be kept out of reach of children and not transferred to other containers.

Serious side effects

Urticaria, severe swelling (edema), anaphylaxis, hypersensitivity reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), drug reaction with eosinophilia and systemic symptoms (DRESS), severe skin reactions including erythema multiforme (SCARs), drug-induced liver injury, hepatitis, pancreatitis, renal failure, kidney damage, liver dysfunction, myopathy, rhabdomyolysis

Mild side effects

• Fatigue
• abdominal pain
• diarrhea
• viral infections
• pharyngitis
• sinusitis
• arthralgia
• low back pain
• cough
• dizziness

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. Additionally, it is best to keep the medication at room temperature between 1°C and 30°C, avoiding excessively hot or cold places. Proper storage will help maintain the drug's effectiveness for a longer period.

Appearance

White to nearly white rectangular tablet

Package unit

30 tablets (10 tablets/PTP x 3)