Delcox Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be administered regardless of meals. 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg per dose twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks of treatment with 400 mg per day, another treatment method should be considered. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib, with an additional 200 mg on the first day of administration if needed. From the second day of administration, the recommended dose, if needed, is 200 mg per dose twice daily. Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may increase the risk of gastrointestinal bleeding in individuals who regularly consume more than three alcoholic beverages a day, so consultation with a doctor or pharmacist is necessary. This drug may increase the risk of serious cardiovascular issues, including thrombosis, myocardial infarction, and stroke. Therefore, if there is a history or risk factors for cardiovascular disease, it should be used at the minimum dosage for the shortest possible duration. This drug can cause serious gastrointestinal side effects such as perforation, ulcers, and bleeding, requiring special caution for patients with a history of gastrointestinal disorders or the elderly. Seek immediate medical attention if symptoms like epigastric pain, dyspepsia, black stool, or hematemesis occur. This medication should not be administered to patients with specific allergy histories, severe liver or kidney impairment, active peptic ulcer disease, heart failure, pregnant or breastfeeding women. Patients with impaired liver or kidney function, asthma, hypertension, heart failure, edema, and the elderly should take this medication cautiously and may require regular assessments. This drug can cause various adverse reactions, with common reports of dyspepsia, headaches, dizziness, hypertension, skin rash, edema, and fluid retention. In severe cases, there is a risk of hepatitis, myocardial infarction, stroke, vasculitis, and deterioration of kidney function, so any emerging symptoms should be discussed with healthcare professionals immediately. This drug can interact with other medications, especially those metabolized by the liver, antihypertensives, diuretics, anticoagulants, and antidepressants, so inform your physician when taking these. Pregnant women or those who might become pregnant should not take this medication, and if pregnancy is confirmed during use, it should be stopped immediately and medical personnel consulted. This drug may also be excreted in breast milk, so breastfeeding women should avoid taking this or stop breastfeeding. The safety and efficacy for children and adolescents have not been established; therefore, it should not be administered to those under 18 years of age. Elderly individuals have a higher likelihood of compromised kidney, liver, and heart function, necessitating extra caution when taking this drug and possible dosage adjustments. For those taking this medication for an extended period, regular blood tests and liver and kidney function assessments are required, with immediate discontinuation if any abnormal signs are detected. Overdose can lead to symptoms such as lethargy, drowsiness, nausea, vomiting, and abdominal pain, necessitating immediate emergency treatment. This medication should be kept out of reach of children, and it is advisable to avoid transferring it to other containers.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechial hemorrhage, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, appetite loss, increased appetite, depression, neuro-excitability, drowsiness, fatal intracranial hemorrhage, hallucinations, epilepsy exacerbation, upper respiratory infections, bronchospasm, exacerbated bronchospasm, dyspnea, laryngitis, pneumonia, nosebleed, voice disorder, vesicular dermatitis, dermatitis, nail disorders, photosensitivity reactions, pruritus, erythematous rash, maculopapular rash, skin disorders, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, mucous membrane syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash, arrhythmia, left ventricular hypertrophy, angina, unstable angina, coronary artery disorder, myocardial infarction, heart failure, palpitations, tachycardia, aortic valve regurgitation, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombophlebitis, vasculitis, deep vein thrombosis, intracerebral hemorrhage, furuncle, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, ear pain, hearing impairment, liver function abnormalities, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, synovial cyst, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fracture, tendon rupture, decreased hematocrit, increased hemoglobin, nosebleed, thrombocytopathic disease, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, bursitis, contact dermatitis, injection site reaction, dermal nodules, taste impairment, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual confusion, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reaction, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, photosensitive reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, menstrual disorders

Store this medication in a tightly sealed container to prevent air ingress, ideally at room temperature between 15 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance

A white capsule filled with powder, with yellow stripes on the upper and lower parts.

Package unit

30 capsules/bottle, 100 capsules/bottle