Doneranz 5 mg (Donepezil Hydrochloride Hydrate)

Adult dose

As donepezil hydrochloride, administer 5 mg once daily before bedtime. After administering 5 mg for 4-6 weeks, assess clinical response to determine if dosage can be increased to 10 mg. Caution is advised regarding gastrointestinal adverse reactions when increasing to 10 mg per day. For underweight female patients over 85 years old, daily dosage should not exceed 5 mg.

Child dose

There is no experience using this medication in pediatric patients.

This medication contains donepezil hydrochloride as the main ingredient, and is used to treat symptoms of Alzheimer's type dementia. This medication should not be used by certain patients. For example, individuals who have allergies to this medication or its components, women who are pregnant or may become pregnant, nursing mothers, and patients with lactose intolerance or certain genetic metabolic disorders should not take this medication. Patients with heart disease, those with a history of peptic ulcer, asthma or chronic obstructive pulmonary disease, and patients with extrapyramidal disorders such as Parkinson's disease should be cautious when using this medication, as it may slow heart rate or exacerbate gastrointestinal disorders. Serious side effects such as fainting, heart irregularities, gastrointestinal bleeding, liver dysfunction, seizures, muscle problems, respiratory distress, acute pancreatitis, and acute renal failure may occur during treatment with this medication, and patients should consult medical personnel immediately if these symptoms arise. Additionally, this medication can cause a variety of side effects such as dizziness, nausea, vomiting, diarrhea, insomnia, hallucinations, depression, myalgia, and should be monitored closely for changes in symptoms during use. This medication can affect heart rhythm, so patients with heart conditions or prolonged QT intervals should confirm their conditions through ECG before use. Caution is required during the initial administration or dose adjustment, as it may affect driving or operating machinery. It is advisable for pregnant or nursing women to avoid taking this medication, and if needed, to consult with medical professionals about discontinuing breastfeeding. This medication can interact with various drugs, so patients taking other medications must inform their doctor or pharmacist. In the event of an overdose, dangerous symptoms such as nausea, vomiting, bradycardia, and respiratory depression may occur, so immediate hospital visit is necessary and atropine may be used as an antidote. This medication should be kept out of reach of children, and changing the storage container may affect product quality, so it should be avoided.

Serious side effects

Rash, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash accompanied by high fever, blistering, skin sloughing, pain in oral or eye mucosa, breathlessness or difficulty breathing, asthma attacks, respiratory abnormalities coupled with cough and fever, jaundice (yellowing of the skin or eyes), extreme heaviness throughout the body, sudden and severe headaches, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• dizziness
• insomnia
• drowsiness
• anxiety

This medication should be stored in an airtight container that allows for good air circulation, preferably at room temperature between 1°C and 30°C. Storing it this way helps maintain the medication's effectiveness and prevents deterioration.

Appearance

This medication is a white, round film-coated tablet.

Package unit

30 tablets/bottle - 30 tablets/bottle