Tragliflozin Duo Tablet 2.5/850mg

Adult dose

This medication is administered twice daily with meals. To minimize gastrointestinal side effects associated with metformin, dose increases should be gradual. 1. For patients not currently treated with metformin: Start with an initial dose of this medication at 2.5/500 mg twice daily, one tablet per dose, with the option to increase to 2.5/1000 mg twice daily, one tablet per dose. 2. For metformin users:

This medication helps control blood sugar levels. However, during this treatment, there is a risk of serious side effects such as lactic acidosis. Lactic acidosis is a condition caused by excessive accumulation of lactate in the body, which can be life-threatening if not treated immediately. This medication should not be administered to patients with certain conditions. For example, individuals allergic to the components of this drug, those with type 1 diabetes, patients with severe renal impairment, acute heart diseases, liver dysfunction, pregnant or breastfeeding women should not take this medication. When using it in conjunction with other hypoglycemic agents that pose a risk of hypoglycemia, particular caution should be taken for symptoms of low blood sugar, and the dosages of other medications may need to be adjusted as necessary. Patients with decreased renal function should undergo regular kidney function tests, and the medication should not be taken if kidney function is severely compromised. Patients with unstable heart function or those with acute heart diseases should use this medication cautiously. In cases where iodinated contrast media is administered during radiological examinations, the use of this medication should be paused before and after the contrast agent administration until renal function stabilizes. For patients undergoing surgery, the medication should be discontinued 48 hours prior to the procedure and can be resumed after confirming normal recovery of kidney function. During the treatment with this medication, acute pancreatitis or skin blistering diseases may occur, so if symptoms such as abdominal pain or skin abnormalities appear, immediate consultation with a doctor is necessary. This medication may lower vitamin B12 levels, so regular checks for vitamin B12 deficiency are needed for long-term use. Pregnant women or those planning to conceive should avoid using this medication, and breastfeeding women are also advised against it. Safety in children and adolescents has not been established, so it should not be used in children under 10 years of age. Elderly patients commonly have decreased renal function; therefore, treatment should be conducted at the minimum dose while regularly monitoring renal function during usage. There is insufficient research on the effects of this medication on driving and operating machinery, so caution is required during use. In case of overdose, treatments such as removing the drug from the gastrointestinal tract or dialysis may be necessary. This medication should be stored in a tightly closed container, avoiding moisture and direct sunlight, and should not be transferred to another container.

Serious side effects

Urticaria, angioedema, lactic acidosis, pancreatitis, blistering dermatosis, abnormal liver function (abnormal liver function tests, hepatitis), angina pectoris, acute myocardial infarction, unstable angina, congestive heart failure, cardiac arrest, pneumonia, respiratory distress, asthma, acute kidney injury, end-stage renal disease, cerebral infarction, seizures, severe rash with fever, blistering, skin shedding, oral/ocular mucosal pain, chest tightness, difficulty breathing, cold sweat, paleness.

Mild side effects

• Nasopharyngitis
• hypersensitivity
• hypoglycemia
• taste disturbances
• cough
• decreased appetite
• diarrhea
• constipation
• nausea
• vomiting

This medication should be stored in a tightly closed container to protect it from air and moisture. Recommended storage temperature is between 1 and 30 degrees Celsius, to maintain the effectiveness of the drug for a longer period.

Appearance

Bright orange, bilaterally convex oval film-coated tablet

Package unit

10 tablets/bottle, 30 tablets/bottle, 60 tablets/bottle, 100 tablets/bottle, 200 tablets/bottle, 30 tablets/box (10 tablets/PTP x 3)