Glymepiride Tablets 2mg (Glymepiride)

Adult dose

Adjusted individually for each patient. This medication is taken orally once daily, before breakfast or just before the first meal. The initial dose is 1 mg once daily, increasing by 1 mg at intervals of 1–2 weeks as needed. Generally, doses above 4 mg provide little additional effect, but some patients may increase to 6 mg or 8 mg. If 4 mg daily fails, consider a switch to insulin therapy before considering the combination with insulin or other oral hypoglycemics.

This medication is not to be used in patients with insulin-dependent diabetes or in patients with diabetic ketoacidosis or in a comatose state. Additionally, those who have had an allergic reaction to this medication or sulfonylureas should not take it. There is no experience with this medication in patients with severely impaired liver or kidney function, and in such cases transitioning to insulin therapy is recommended. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication. In patients with severe infections or those undergoing surgery or with severe trauma, insulin therapy is more appropriate. Patients with gastrointestinal disorders like diarrhea or vomiting should be cautious as food absorption may be inadequate, increasing the risk of hypoglycemia. This medication contains lactose, and individuals with certain genetic metabolic disorders should not take it. During the first week of dosing, the risk of hypoglycemia is increased, so blood sugar levels must be carefully monitored, especially in elderly patients, those with poor nutritional status or irregular eating habits, and those with impaired kidney or liver function. Those who frequently consume alcohol or take other medications simultaneously may also have an increased risk of hypoglycemia, so consult a physician. This medication contains Yellow No. 4 dye, and those allergic to this ingredient should use it cautiously. Symptoms of hypoglycemia may include headache, severe hunger, nausea, fatigue, drowsiness, confusion, and in severe cases, loss of consciousness; if these symptoms occur, quickly consume sugar or inform a healthcare professional. Temporary blurred vision can occur, and gastrointestinal disorders, liver function abnormalities, and changes in blood cell counts have also been reported. Allergic reactions may include skin rashes, itching, and in severe cases, breathing difficulties or shock, so if symptoms appear, discontinue use immediately and consult a hospital. This medication must be combined with dietary therapy and exercise for blood sugar control, and regular intake is important. If hypoglycemia occurs, sugar should be quickly consumed, and artificial sweeteners will not be effective, so caution is needed. When receiving treatment at another hospital or pharmacy, be sure to inform them of this medication, and during stressful situations or surgeries, blood sugar management methods may change, so consult a physician. In the case of an overdose, hypoglycemia may lead to a comatose state, requiring immediate emergency treatment, and after use, proper storage away from children's reach is essential.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, jaundice (yellowing of the skin or eyes), extreme lethargy, thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, agranulocytosis, pancytopenia, anaphylaxis, angioedema, skin and mucous membrane syndrome (Stevens-Johnson syndrome), shock, liver dysfunction (bile secretion disorders, jaundice), hepatitis, cerebral convulsions, confusion of consciousness, severe hypoglycemia

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggression
• decreased concentration
• decreased agility or drive

This medication should be stored in a sealed container to protect it from air or moisture, and it is safest to store at room temperature between 1°C and 30°C.

Appearance

Green rectangular tablets

Package unit

30 tablets/bottle, 300 tablets/bottle