Widercox Capsule 100 Milligrams (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted for each patient. It may be taken with or without food. 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks at 400 mg per day, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day if needed. From the second day of administration, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may increase the risk of gastrointestinal bleeding when taken by individuals who regularly consume more than three drinks a day; therefore, it should be discussed with a doctor or pharmacist. This medication may increase the risk of serious cardiovascular problems such as thrombus, myocardial infarction, and stroke; hence, it should be used at the lowest effective dose for the shortest duration. There can be serious gastrointestinal adverse reactions, such as perforation, ulceration, and bleeding, especially in the elderly or those with a history of gastrointestinal diseases. This medication should not be administered to patients with specific allergies or conditions, such as sulfonamide allergy, severe liver or kidney impairment, active peptic ulcer, heart failure, or pregnant women. Patients with decreased liver or kidney function, asthma, a history of hypertension, cardiovascular disease, and the elderly should use this medication cautiously and undergo regular monitoring as directed by their doctor. Various adverse reactions such as dyspepsia, abdominal pain, headache, dizziness, hypertension, skin rash can occur during the intake of this drug, so if symptoms are severe or persistent, consult a doctor immediately. This drug may affect liver and kidney function, requiring regular blood tests and liver and kidney function tests; treatment should be discontinued if abnormal findings occur. Pregnant women or those who may become pregnant, and breastfeeding women should not take this medication, and if pregnancy is confirmed during use, it should be immediately stopped. This drug can interact with other medications; therefore, especially when taking antihypertensives, anticoagulants, diuretics, or antidepressants, inform your doctor and observe carefully. In case of overdose, symptoms such as nausea, vomiting, drowsiness, and gastrointestinal bleeding may present, and immediate medical attention should be sought. The safety and efficacy of this medication have not been established in children and adolescents, so its use is not advisable. Elderly patients may have a higher risk of renal and hepatic impairment, so dosage adjustment and status monitoring are necessary when taking this medication. This drug should be kept out of reach of children, and it is advisable not to transfer it to another container.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tracts, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, bowel perforation, pancreatitis, liver enzyme elevation, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illness, injury, folliculitis, contact dermatitis, injection site reactions, skin nodules, taste disorder, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infections, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, leg cramps, tension hypertension, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormality, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, anorexia, increased appetite, depression, neurological hypersensitivity, drowsiness, fatal intracranial hemorrhage, hallucination, worsening of epilepsy, bronchospasm, exacerbating bronchospasm, shortness of breath, laryngitis, pneumonia, nosebleed, voice disorder, vesicular dermatitis, dermatitis, nail disease, photosensitivity reactions, erythematous rash, papular rash, skin disease, dry skin, excessive sweating, erythema multiforme, exfoliative dermatitis, mucocutaneous syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechial hemorrhage, dandruff, drug rash, sepsis, sudden death, anaphylactic-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, acute renal failure, hyponatremia, menstrual disorders, female infertility, chest pain, thirst, ulcerative stomatitis, gastritis, allergy, low back pain, hyperlipidemia, diabetes, weight gain, fracture, arthralgia, RA factor positive, shingles, hearing loss

This medication should be stored in a tightly closed container to prevent air ingress. It is also important to keep it at room temperature between 15 and 30 degrees Celsius. This way, the effectiveness of the medication can be safely maintained.

Appearance

White to yellowish powder filled in a white capsule with a blue stripe on the top and bottom

Package unit

30 capsules/bottle, 100 capsules/bottle