Medication info
Rapudin Tablet 10 mg (Rabeprazole)

Rapudin Tablet 10 mg (Rabeprazole)

Prescription medicationTabletOral
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Phurim Pharmaceutical Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201901970 · Approved 2019.04.01 · Insurance code 649001960

Summary

Main use
Treatment of gastrointestinal diseases (e.g., ulcers and gastritis), preanesthetic medication, and adjunctive treatment for Helicobacter pylori eradication
Who takes it
Adults
Adult dose
1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally per dose, twice daily in the morning and before bedtime. Administer for up to 8 weeks. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally per dose, twice daily in the morning and before bedtime. Administer for up to 6 weeks. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. Administer for up to 2 weeks. 4. Combination therapy with antibiotics in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before administration of anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine per dose, twice daily.

Ingredients

Manufacturer
Phurim Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal diseases (e.g., ulcers and gastritis), preanesthetic medication, and adjunctive treatment for Helicobacter pylori eradication

  • Gastric ulcer
  • duodenal ulcer
  • gastric mucosal lesions from acute gastritis
  • chronic gastritis
  • peptic ulcer
  • gastroesophageal reflux disease
View approved original text

This medication is used to treat gastric ulcers and duodenal ulcers, as well as to improve gastric mucosal damage caused by acute and chronic gastritis. It is also used in combination with antibiotics to enhance the effectiveness of treatment for patients with peptic ulcers associated with Helicobacter pylori infection. This medication is also used for preoperative dosing and helps in treating gastroesophageal reflux disease. It effectively improves symptoms and lesions related to various gastrointestinal disorders.

How to take

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally per dose, twice daily in the morning and before bedtime. Administer for up to 8 weeks. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally per dose, twice daily in the morning and before bedtime. Administer for up to 6 weeks. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. Administer for up to 2 weeks. 4. Combination therapy with antibiotics in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before administration of anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine per dose, twice daily.

Precautions

This medication should not be used by patients allergic to specific ingredients. It contains lactose, so individuals with a genetic disorder that impairs lactose digestion should also avoid this medication. Patients allergic to soybean oil, soy, or peanuts should also avoid this medication. Careful use is recommended for patients with a history of drug allergies, liver or kidney dysfunction, those undergoing dialysis, the elderly, and patients with abnormal lipid metabolism. This medication can cause severe allergic reactions or symptoms of anaphylaxis; in the event of symptoms such as facial pallor, decreased blood pressure, or difficulty breathing, the patient should immediately discontinue use and seek medical attention. As liver function abnormalities may occur, the medication should be stopped and a doctor's evaluation should be sought if liver enzyme levels rise or jaundice symptoms develop. Severe side effects such as agranulocytosis or thrombocytopenia may occur suddenly, so if symptoms such as sore throat, extreme fatigue, or fever appear, the patient should stop taking the medication immediately. Other rare but severe side effects reported include skin rash, convulsions, and heart rhythm abnormalities, which should be discussed with a doctor if noticed. While taking this medication, symptoms such as indigestion, headache, insomnia, dizziness, vomiting, and constipation may occur, and if these symptoms persist, medical personnel should be informed. If stomach cancer or malignant tumors are suspected, diagnosis could be delayed due to this medication, so tests should be performed if symptoms such as weight loss, recurrent vomiting, or hematemesis occur. If there is no treatment effect or if the condition worsens, it may be necessary to switch to other treatment methods. Elderly patients may have reduced physical function, so dosages and intervals should be adjusted, and their condition should be monitored closely. Dialysis patients may experience increased drug concentrations in the blood, so starting at a lower dosage is recommended. Pregnant women or those who may become pregnant should use this medication only when the benefits outweigh the risks, as determined by a doctor. Nursing mothers should refrain from taking this medication, as it may be excreted in breast milk. Safety in pediatric patients is not established, and use is not recommended. This medication should be stored out of reach of children and kept in its original container for safety.

Side effects

  • Shock
  • symptoms of anaphylaxis
  • facial pallor
  • hypotension
  • generalized rash
  • dyspnea
  • hepatic dysfunction
  • jaundice
  • agranulocytosis
  • pharyngitis
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  • systemic fatigue
  • fever
  • thrombocytopenia
  • pancytopenia
  • aplastic anemia
  • convulsions
  • interstitial nephritis
  • Stevens-Johnson syndrome
  • Reiter's syndrome
  • rhabdomyolysis
  • heart block
  • heart failure
  • constipation
  • diarrhea
  • hard stool
  • nausea
  • vomiting
  • abdominal distension
  • loss of appetite
  • headache
  • insomnia
  • drowsiness
  • reversible confusional state
  • hallucinations
  • consciousness disturbance
  • dizziness
  • chills
  • heat sensation
  • facial flushing
  • leukocytosis
  • eosinophilia
  • leukopenia
  • erythropenia
  • hematocrit reduction
  • ALT elevation
  • AST elevation
  • Al-P elevation
  • γ-GTP elevation
  • T-Bil elevation
  • LDH elevation
  • TTT elevation
  • urine protein abnormality
  • BUN elevation
  • serum uric acid elevation
  • Cl elevation
  • delay in physiological maturation
  • Na elevation
  • K decrease
  • gynecomastia
  • edema
  • fatigue
  • glossitis
  • headache
  • urticaria
  • skin rash
  • abdominal pain
  • dyspepsia
  • enteritis
  • gastric ulcer
  • erosive gastritis
  • duodenitis
  • bloating
  • nasopharyngitis
  • upper respiratory tract infection
  • bronchopneumonia
  • tinea
  • cough
  • oropharyngeal pain
  • oropharyngeal discomfort
  • wet cough
  • fatigue
  • chest pain
  • limb pain
  • joint pain
  • neck pain
  • pruritus
  • acne
  • contusion
  • insomnia
  • non-alcoholic steatohepatitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The recommended storage temperature is room temperature between 1 to 30 degrees Celsius. Proper storage can prolong the effectiveness of the medication.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.