Tutension Tablet 5 mg (Esamlodipine Besilate Hydrate)

Adult dose

For esamlodipine, the usual dosage is 2.5 mg orally once daily, which may be increased up to 5 mg daily based on patient response. This medication should be taken with an adequate amount of water. Adjustments should be made appropriately based on symptoms.

This medication should not be used in certain patients. Individuals who have had allergies to this drug, its components, or similar classes of drugs should not take it. Pregnant women or those who may become pregnant, as well as nursing mothers, should also avoid this medication. Patients in a state of cardiac shock, those with severe heart valve issues, unstable angina patients, and those who have recently had a myocardial infarction may face risks from using this drug. Patients with severe liver dysfunction or hypotension should also avoid this medication. Additionally, those with lactose intolerance or certain genetic metabolic disorders should not take this drug. Patients with significantly impaired kidney function, the elderly, those with acute heart failure, patients experiencing sudden hypertension, and those with mild to moderate liver dysfunction should use this medication with caution. During treatment, flushing, warmth, fatigue, or swelling may occur. Rapid heartbeat, dizziness, headaches, discomfort, or nausea may also present. Drowsiness or ankle swelling has been reported as well. Rarely, dry mouth or excessive sweating may occur, and blood pressure may drop too low or fainting may happen. Allergic reactions such as skin rash, itching, or hair loss may rarely occur, so if there are any unusual symptoms, immediate consultation with a physician is necessary. This medication should not be abruptly discontinued, as it can worsen symptoms. Patients with compromised liver function may require dosage adjustment as the drug may remain in the body longer. When experiencing low blood pressure or dizziness, it is advisable to avoid driving or operating dangerous machinery. Interactions may occur when taken with other antihypertensives or certain antibiotics, analgesics, etc., so if taking other medications, it is essential to inform your doctor or pharmacist. Particularly, caution is needed when taken with grapefruit juice, as it may enhance the drug's efficacy. If pregnant or nursing, the safety of this medication is not well established, and it is recommended to discontinue breastfeeding. Children aged 6 years and older may use this medication, while its effectiveness in those under 6 years has not been confirmed. The elderly may have higher drug concentrations in the body, so careful dosing starting with a lower dose is advised. In cases of overdose, blood pressure may drop too low, and cardiac irregularities or shock may ensue, requiring immediate emergency treatment. In such instances, monitoring blood pressure and cardiac status closely in a hospital setting is necessary for appropriate intervention. This medication should be kept out of reach of children, and transferring it to another container is not recommended.

Serious side effects

Urticaria, angioedema, toxic epidermal necrolysis, jaundice, severe allergic reactions, severe dermatological reactions, liver dysfunction (jaundice), paralysis, seizures, severe neurological symptoms, significant edema or urinary abnormalities.

Mild side effects

• Flushing with warmth
• fatigue
• edema
• palpitations
• dizziness
• headache
• migraine
• weakness
• abdominal pain
• nausea

This medication should be stored in a tightly closed container to avoid exposure to air and moisture, and it is safest to keep it at room temperature between 1 degree and 30 degrees Celsius. Storing it this way will maintain the drug's effectiveness and prevent degradation.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle