Medication info
Seoul Lapatidine Tablet

Seoul Lapatidine Tablet

Prescription medicationTablet
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Seoul Pharmaceutical Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201901881 · Approved 2019.03.28 · Insurance code 652904190

Summary

Main use
Treatment of gastrointestinal disorders (ulcers, gastritis, and esophagitis); preanesthetic medication; use in combination therapy for eradication
Who uses it
Adults
Adult dosage
1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks, although healing time may vary in some patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks, although healing time may vary in some patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks, although healing time may vary in some patients. 4. Combination therapy with antibiotics in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg per dose orally twice daily.

Ingredients

Manufacturer
Seoul Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal disorders (ulcers, gastritis, and esophagitis); preanesthetic medication; use in combination therapy for eradication

  • Gastric ulcers
  • duodenal ulcers
  • acute gastritis
  • chronic gastritis mucosal lesions
  • peptic ulcers
  • gastroesophageal reflux disease
View approved original text

This medication is used for the treatment of gastric ulcers and duodenal ulcers and improves gastric mucosal damage caused by acute and chronic gastritis. It also enhances the treatment effect when combined with antibiotics for patients with peptic ulcers accompanied by Helicobacter pylori infection. Taking it before anesthesia can prevent the backward flow of stomach contents into the airway. Additionally, it is effective in the treatment of gastroesophageal reflux disease. This medication is used to improve and treat symptoms overall related to gastrointestinal disorders.

Dosage and Administration

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks, although healing time may vary in some patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks, although healing time may vary in some patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks, although healing time may vary in some patients. 4. Combination therapy with antibiotics in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg per dose orally twice daily.

Precautions

This medication should not be used by individuals who are allergic to any of its components. It contains lactose; therefore, patients who are genetically unable to digest lactose or have glucose-galactose malabsorption disorders should avoid using it. Patients who are allergic to soybean oil, soybeans, or peanuts should also refrain from taking this medication. Those who have a history of hypersensitivity reactions to drugs should use it with caution. Patients with liver or kidney problems, especially those on dialysis and older adults, should take it with caution. Patients with lipid metabolism disorders such as hyperlipidemia, diabetic dyslipidemia, or pancreatitis should also use this medication with caution. This medication may rarely cause severe allergic reactions, liver dysfunction, and blood cell reductions as side effects; therefore, if symptoms appear, treatment should be stopped immediately, and medical attention should be sought. Mild side effects such as headaches, insomnia, dizziness, indigestion, abdominal pain, nausea, and constipation have also been reported; patients should be vigilant for these symptoms. Especially, if there are symptoms suspicious of gastric cancer or malignant tumors, tests should be conducted before using this medication, and if a malignant tumor is confirmed, treatment should be discontinued. During treatment, regular blood, liver, and kidney function tests should be conducted to check for abnormalities. Older adults should be monitored carefully and dosages adjusted based on physical function decline. Pregnant women or those who may become pregnant should only use it under a physician's judgment, and breastfeeding women are advised not to take this medication as it may be excreted in breast milk. Safety in children has not been established, so caution is needed in usage. This medication should be kept out of the reach of children and stored in its original container to prevent misuse or deterioration.

Side effects

  • Shock
  • symptoms of anaphylaxis
  • facial pallor
  • hypotension
  • generalized rash
  • difficulty breathing
  • liver dysfunction
  • jaundice
  • agranulocytosis
  • pharyngitis
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  • generalized fatigue
  • fever
  • thrombocytopenia
  • pancytopenia
  • aplastic anemia
  • seizures
  • interstitial nephritis
  • Stevens-Johnson syndrome
  • Lyell syndrome
  • rhabdomyolysis
  • heart block
  • heart failure
  • constipation
  • diarrhea
  • hard stools
  • nausea
  • vomiting
  • abdominal distension
  • loss of appetite
  • headache
  • insomnia
  • drowsiness
  • reversible confusional state
  • hallucinations
  • consciousness disturbance
  • dizziness
  • chills
  • heat sensation
  • facial flushing
  • leukocytosis
  • eosinophilia
  • leukopenia
  • erythrocytopenia
  • decreased hematocrit
  • elevated ALT
  • elevated AST
  • elevated Al-P
  • elevated γ-GTP
  • elevated T-Bil
  • elevated LDH
  • elevated TTT
  • abnormal urinary protein
  • elevated BUN
  • elevated serum uric acid
  • elevated Cl
  • delayed biological response
  • elevated Na
  • decreased K
  • gynecomastia
  • edema
  • fatigue
  • glossitis
  • headache
  • urticaria
  • skin rash
  • abdominal pain
  • dyspepsia
  • enteritis
  • gastric ulcer
  • erosive gastritis
  • duodenitis
  • bloating
  • rhinosinusitis
  • upper respiratory infection
  • bronchopneumonia
  • tinea
  • cough
  • oropharyngeal pain
  • oropharyngeal discomfort
  • wet cough
  • fatigue
  • chest pain
  • limb pain
  • arthralgia
  • cervical pain
  • pruritus
  • acne
  • contusion
  • insomnia
  • non-alcoholic fatty liver hepatitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture; therefore, it is important to store it in a tightly sealed container. Also, it should be kept at room temperature, between 1 degree and 30 degrees Celsius, away from extreme cold or heat to safely maintain its efficacy.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.