IVISC Plus Injection (Sodium Hyaluronate) (Pre-filled)

Adult dosage

1. Cataract surgery and intraocular lens implantation: Slowly inject the required amount into the anterior chamber before or after lens removal using a needle or cannula. Administer before intraocular and extraocular cataract surgery. 2. Corneal transplant surgery: After removing the corneal graft, fill the anterior chamber with this medication until it matches the corneal surface and then place and suture the donor graft on top of it. 3. Glaucoma filtering surgery: Inject this medication through a keratocentesis to supplement and maintain the anterior chamber volume.

This medication contains sodium hyaluronate and is primarily used after eye surgery. However, it should not be administered to patients who have had allergies to this ingredient or to protein-based medications. Temporary increases in intraocular pressure may occur, and rarely, inflammation, corneal edema, corneal opacity, bleeding, and iris-related issues may arise. Symptoms such as eye pain, itching, and blurred vision may also appear. Care should be taken to closely monitor intraocular pressure after surgery, and appropriate treatment is needed if the pressure rises. It is advisable to wash or aspirate this medication after surgery, if possible. Before performing ultrasonic emulsification and aspiration surgery, the drug must be evenly distributed in the eye through aspiration irrigation. When cleaning surgical tools, solutions containing chemicals that may react with this medication should not be used. Precautions should be taken as this drug is extracted from avian cells, which may pose a risk of immune responses or other hazards. It should not be used in conjunction with hyaluronidase, and must only be utilized according to specified methods and dosages for ophthalmic use. It must never be injected intravascularly. Prior to use, the refrigerated medication should be left at room temperature for about 30 minutes to allow it to reach the proper temperature, and any unused portion after opening should be disposed of. When using the drug mixed with air, care must be taken to prevent air from entering beneath the iris, and injection should be done slowly and cautiously. Excessive injection into the anterior chamber may cause an increase in intraocular pressure, so only an appropriate amount should be used. This medication should be stored out of the reach of children, protected from direct sunlight, in a cool and dry, sealed container. Additionally, it is important not to transfer it to another container to maintain its quality.

Mild side effects

Increased intraocular pressure, inflammatory responses, corneal edema, corneal opacity, anterior segment bleeding, neovascularization of the iris, posterior chamber ulcers, conjunctival adhesion failure, mydriasis, lens opacity, pain, itching, blurred vision, corneal functional disorders, opacification of the intraocular lens surface, corneal calcification.

This medication should be stored in a sealed container to prevent exposure to air, at a cool temperature between 2 degrees and 8 degrees. It should be stored away from direct sunlight, and care should be taken to prevent freezing.

Appearance

A colorless, transparent, and viscous liquid contained in a glass vial capped with rubber at both ends (part of the pre-filled syringe system).

Package unit

0.85mL/vial