Cebrec Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be administered with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks at 400 mg daily, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This drug may increase the risk of gastrointestinal bleeding if taken by individuals who consume alcohol daily, so consultation with a doctor or pharmacist is essential. It may worsen cardiovascular issues, so individuals with cardiovascular diseases or risk factors should use the minimal dose for the shortest duration, and report any symptoms to medical personnel immediately. Because it may cause ulcers or bleeding in the gastrointestinal tract, elderly individuals or those with a history of gastrointestinal diseases should be carefully monitored, and should seek immediate treatment if they experience symptoms such as abdominal pain, indigestion, black stools, or vomiting blood. This medication should not be administered to specific allergic individuals or those with liver or kidney diseases, heart diseases, pregnant women, and nursing mothers; such cases must be disclosed to medical personnel. Patients with impaired liver or kidney function, asthma, hypertension, heart failure, or diabetes should use this medication more cautiously and must regularly check their condition. Dizziness or drowsiness may occur during the use of this drug; thus, caution is advised when driving or operating machinery. There are many interactions with other medications, so individuals taking other drugs must inform medical personnel, particularly when taking antihypertensives, anticoagulants, diuretics, antidepressants, etc. Women planning for pregnancy or who may be pregnant should discuss the potential impact of this medication on reproductive capacity with medical personnel, and avoid use during pregnancy. Regular blood tests and liver and kidney function tests should be conducted during long-term use to monitor for any unusual signs. In case of overdose, symptoms such as lethargy, nausea, vomiting, and abdominal pain may occur, and immediate medical attention is required.

Gastrointestinal bleeding, cardiovascular thrombotic response, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual clouding, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, osteopathy, myalgia, cervical stiffness, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various areas, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reactions, dermatological nodules, headache, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergy exacerbation, allergic reaction, lethargy, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, angioedema, insomnia, loss of appetite, increased appetite, depression, neurotic response, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory infection, bronchospasm, exacerbation of bronchospasm, dyspnea, laryngitis, pneumonia, epistaxis, voice disorder, vesicular dermatitis, dermatitis, nail disease, photosensitivity reactions, pruritus, erythematous rash, papular rash, skin disease, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, mucous membrane syndrome, toxic epidermal necrolysis, petechiae, dandruff, drug rash, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, acute renal failure, tubulo-interstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, menstrual disorders, female infertility, chest pain, anaphylactic reactions, hallucinations, cerebral hemorrhage

This medication should be stored in a tightly sealed container to prevent air infiltration, and the optimal temperature for storage is between 15 and 30 degrees Celsius at room temperature. Proper storage helps maintain the efficacy of the medication for a longer period.

Appearance

A white capsule filled with a white to off-white powder with blue lines on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle