Donepezil Hydrochloride Orally Disintegrating Tablet 10 mg

Adult dose

As Donepezil Hydrochloride, administer 5 mg once daily before bedtime. For 4 to 6 weeks, administer a dose of 5 mg. After evaluating clinical response during this period, the dose may be increased to 10 mg. When increasing to 10 mg daily, administer with caution regarding gastrointestinal adverse reactions. This medication is an orally disintegrating tablet that can be placed on the tongue and taken with or without water.

Child dose

There is no experience with the use in children.

This medication should not be used in patients who are hypersensitive to specific ingredients or in women who are pregnant or breastfeeding. Patients with heart disease or heart rhythm issues should use this medication with caution and be alert for cardiac symptoms. Patients with a history of peptic ulcers or who are taking non-steroidal anti-inflammatory drugs should closely monitor their gastrointestinal condition. Patients with asthma or obstructive lung disease should be cautious as this medication might exacerbate respiratory symptoms. Patients with extrapyramidal disorders such as Parkinson's disease should administer this medication carefully due to the possibility of worsening symptoms. This medication can slow down heart rate or cause arrhythmias; therefore, regular monitoring of cardiovascular status is necessary. Severe side effects such as gastrointestinal bleeding, liver dysfunction, seizures, and muscle disorders may occur, so immediate consultation with healthcare providers is required if any unusual symptoms appear. Caution is needed when driving or operating machinery as dizziness or drowsiness may occur. There is a high potential for interactions with other medications, so it is essential to inform the healthcare provider or pharmacist of any other medications being taken. It is safest for pregnant or breastfeeding women not to use this medication; if absolutely necessary, it should be discussed with a healthcare professional. Safety in children has not been established, thus it should not be used in pediatric patients. In cases of overdose, symptoms such as nausea, vomiting, muscle weakness, and difficulty breathing may arise, requiring immediate emergency care. This medication is an orally disintegrating tablet; it is important to let it dissolve completely in the mouth before swallowing.

Serious side effects

Syncope, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcer, perforating duodenal perforation, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, cerebral seizures, cerebral hemorrhage, cerebrovascular disorders, extrapyramidal disorders, neuroleptic malignant syndrome, rhabdomyolysis, respiratory distress, acute pancreatitis, acute renal failure, sudden death, severe allergic reactions (urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat).

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• fever
• insomnia
• dizziness
• tremors

Store this medication in a tightly closed container to prevent air or moisture from entering. It is also advisable to keep it at room temperature between 1 and 30 degrees Celsius.

Appearance

Yellow round orally disintegrating tablet

Package unit

30 tablets (10 tablets/PTP) X 3