Lozastar Plus Tablet

Adult dose

The usual dosage for adults is 1 tablet once a day containing 50 mg of losartan potassium/12.5 mg of hydrochlorothiazide. A daily dose exceeding 100 mg of losartan potassium/25 mg of hydrochlorothiazide is not advisable. The dosing regimen is as follows: 1. Initiate therapy with 1 tablet of losartan potassium 50 mg/hydrochlorothiazide 12.5 mg once daily, and if blood pressure is not controlled after 3 weeks of treatment,

Child dose

There is no experience using this medication in children and adolescents; therefore, the losartan-hydrochlorothiazide combination is not administered to this population.

This medication can cause severe harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. It should not be used in patients with an allergy to this drug or its components, severe renal impairment, specific electrolyte disturbances, and some liver diseases or gout. Special caution is required when using this drug in patients with hypotension, kidney issues, liver disease, serum potassium abnormalities, certain vascular disorders, and diabetes. While taking this drug, various side effects such as dizziness, drowsiness, cough, skin rash, and muscle pain may occur; thus, any unusual symptoms should be discussed with a doctor. In particular, this drug can affect potassium levels, so potassium supplements should not be taken without consultation with a physician, and one should be cautious of possible dizziness when starting treatment due to its blood pressure-lowering effects. Furthermore, this drug may react sensitively to sunlight, potentially increasing the risk of skin cancer, so it’s important to reduce sun exposure and to periodically check the skin condition. This drug may interact with other medications, so it’s crucial to inform the doctor of any ongoing medications, and grapefruit juice should be avoided. Women who are pregnant or breastfeeding should avoid this medication, especially during breastfeeding as it may affect the baby, and should consult with a physician before making a decision. The safety of this drug in children and adolescents has not been established, thus it is not used in these populations. Regular blood tests to monitor kidney function and electrolyte status are necessary while taking this medication. Finally, this drug should be kept out of the reach of children and stored in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pale skin, severe rash with fever, blisters, skin peeling, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), profound fatigue, sudden and severe headache, lightning-like headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

Abdominal pain, swelling/edema, palpitations, back pain, dizziness, cough, sinusitis, upper respiratory infection, fatigue/weakness, diarrhea, nausea, headache, bronchitis, pharyngitis, chest pain, facial swelling, fever, orthostatic hypotension, fainting, angina, arrhythmia (atrial fibrillation, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation), cerebrovascular accident, hypotension, myocardial infarction, secondary AV block, anorexia, constipation, toothache, dry mouth, dyspepsia, flatulence, gastritis, vomiting

This medication is sensitive to light and should be stored in a container that restricts light. It is recommended to keep it at room temperature between 1 to 30 degrees Celsius. This will help maintain the effectiveness of the drug for a longer duration.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle