Metopidil Tablets 75 mg (Naphtopidil)

Adult dose

In adults, start with 25mg of naftopidil once daily. If the effect is insufficient, gradually increase the dose to 50～75mg at intervals of 1～2 weeks, administered orally once daily after a meal. The dose may be adjusted as appropriate according to symptoms, but the maximum daily dose is 75mg.

This medication should not be used by individuals who are allergic to any of its ingredients. Additionally, individuals with a hereditary lactose intolerance should not take this medication. Individuals with impaired liver function should take caution as blood concentration of this medication may increase. Those with serious cardiovascular or cerebral vascular issues should use this medication cautiously. Elderly individuals may have reduced liver function, leading to delayed drug excretion, so caution is advised. Patients taking antihypertensives or certain vasodilators (PDE5 inhibitors) should be careful as blood pressure may drop significantly when taken together with this medication. Individuals with orthostatic hypotension also need to take caution when using this medication. Side effects such as dizziness, lightheadedness, low blood pressure, and gastrointestinal discomfort may occur; any unusual symptoms should prompt immediate consultation with a physician. In particular, if serious side effects such as liver dysfunction or loss of consciousness occur, discontinue use immediately and seek treatment. In cases of overdose, there is a risk of dangerously low blood pressure, so the prescribed dosage must be strictly followed. If experiencing dizziness due to orthostatic hypotension when standing up suddenly, changes in posture should be done slowly. During initial dosing or sudden increases in dosage, dizziness or lightheadedness may worsen, so it is advisable to avoid driving or working at heights during these times. If taking antihypertensives in conjunction with this medication, it is important to monitor blood pressure changes and adjust the dosage as necessary. This medication is intended to relieve symptoms, so if it is ineffective, consider alternative treatment options. Keep this medication out of reach of children, and it should be taken out of its packaging for use. Swallowing it whole may cause injury to the esophagus.

• dizziness
• unsteadiness
• lightheadedness
• hypotension
• abdominal discomfort
• liver dysfunction
• jaundice
• syncope
• loss of consciousness
• hypersensitivity

This medication may be sensitive to light, so it should be stored in a tightly closed container that protects it from light. Additionally, it is best to store it at room temperature between 1°C and 30°C, away from extreme heat or cold.

Appearance

Yellowish - light yellow round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle