Medication info

Esamfin Tablets 5mg (Esamlodipine Besylate Hydrate)

Prescription medicationTablet경구Expired
Ingredient · strength
S-Amlodipine Besylate Dihydrate›7.38mg / 1 tablet
Manufacturer / importer
대원제약(주)
Appearance
White octagonal tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Expired

MFDS item code 201901630 · Approved 2019.03.18

This product's status changed to Expired on 2024.03.18. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Effectiveness in treating myocardial ischemia due to hypertension and coronary artery disease (stable angina, variant angina) and in reducing the risk of hospitalization for angina and vascular procedures.
Who takes it
Adults
Adult dose
Take with sufficient water. Administer esamlodipine 2.5 mg orally once daily, and dosage may be increased to a maximum of 5 mg daily based on patient response. Adjust dosage appropriately according to symptoms.

Ingredients

Manufacturer
대원제약(주)

Efficacy & effects

Effectiveness in treating myocardial ischemia due to hypertension and coronary artery disease (stable angina, variant angina) and in reducing the risk of hospitalization for angina and vascular procedures.

  • Hypertension
  • fixed obstruction of coronary arteries
  • vasospasm of coronary circulation
  • myocardial ischemia
  • angina
View approved original text

This medication is used to treat myocardial ischemia caused by hypertension and stable angina, variant angina. Additionally, in patients recently diagnosed with coronary artery disease via angiography who do not have heart failure and have an ejection fraction of 40% or more, it helps reduce the risk of hospitalization due to angina and lowers the risk associated with coronary artery revascularization procedures. Thus, it is effective in improving heart health and preventing related complications.

How to take

Adult dose

Take with sufficient water. Administer esamlodipine 2.5 mg orally once daily, and dosage may be increased to a maximum of 5 mg daily based on patient response. Adjust dosage appropriately according to symptoms.

Precautions

This medication should not be given to certain patients. For instance, those with allergies to this medication or its components, pregnant or nursing women, patients in shock, individuals with severe heart valve disease, patients with unstable angina, those who have recently experienced a myocardial infarction, individuals with severe liver dysfunction, patients with severe hypotension, and those with certain genetic issues like lactose intolerance should avoid this medication. Furthermore, patients with very poor kidney function, elderly individuals, patients with acute heart failure, those in a hypertensive crisis, and patients with mildly to moderately impaired liver function should use this medication with special caution. Various side effects may occur while taking this medication. Initially, facial flushing and warmth may be felt, and fatigue, swelling, a racing heart, dizziness, headache, indigestion, drowsiness, and ankle swelling may also occur. Rarely, dryness of the mouth or increased sweating may occur, blood pressure may drop too low, or heart rhythm abnormalities may develop. If skin rash or allergic reactions appear, the medication should be discontinued immediately. Discontinuing this medication suddenly can worsen symptoms, so the dosage should be reduced gradually under a physician's guidance, and patients should avoid stopping it arbitrarily. It should be taken with plenty of water, and because it may cause dizziness due to low blood pressure, caution is needed when driving or operating machinery. This medication can interact with other drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist. Special caution is necessary when taken with certain antibiotics, antihypertensive agents, antidepressants, nitrates, and some chemotherapy agents or immunosuppressants. If pregnant or nursing, it is advisable to avoid use as its safety has not been established, and nursing should be discontinued if using this medication. For children, effectiveness has only been confirmed in those aged 6 and older, and it should not be used in children under 6. Elderly patients may have increased blood concentrations of this medication, so it should be started at a low dose while monitoring conditions carefully. In case of overdose, symptoms such as severe hypotension, rapid heartbeat, and shock can occur, so immediate medical attention should be sought for appropriate treatment. This medication should be stored out of reach of children and care should be taken not to transfer it to another container.

Side effects and when to seek care immediately

Serious side effects

  • Hives
  • angioedema
  • toxic epidermal necrolysis
  • jaundice
  • paralysis
  • thrombocytopenia
  • leukopenia
  • elevated blood pressure
  • severe edema

Mild side effects

  • Warmth
  • flushing
  • fatigue
  • swelling
  • palpitations
  • dizziness
  • headache
  • migraine
  • weakness
  • abdominal pain
Show 28 more
  • nausea
  • indigestion
  • drowsiness
  • dry mouth
  • increased sweating
  • weakness
  • lethargy
  • pain
  • weight changes
  • chills
  • hypotension
  • postural hypotension
  • postural dizziness
  • peripheral ischemia
  • vasculitis
  • syncope
  • tachycardia
  • peripheral edema
  • tension
  • sensory loss
  • sensory disturbances
  • peripheral neuropathy
  • taste disturbances
  • tremors
  • extrapyramidal disorders
  • erectile dysfunction
  • gynecomastia
  • bowel movement

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to avoid exposure to air or moisture, and it is best kept at a temperature between 1 degree and 30 degrees Celsius at room temperature. Proper storage will safely maintain the effectiveness of the medication.

Appearance and packaging

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.