Osprost Tablet (Limaprost Aldex)

Adult dosage

1. For improvement of ischemic symptoms such as ulcers, pain, and coldness associated with thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally 3 times daily. 2. For improvement of subjective symptoms (lower-limb pain and numbness) and walking ability associated with acquired lumbar spinal stenosis (patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. Adjust the dose as appropriate according to age and symptoms.

This medication must not be used in women who are pregnant or may become pregnant. Additionally, this drug contains lactose, so individuals with a genetic condition that prevents them from breaking down lactose should not use it. Caution is advised for patients with bleeding tendencies or those taking antiplatelet agents, thrombolytics, or anticoagulants. Skin rash or itching as an allergic reaction may occur during use; if such symptoms appear, use should be stopped immediately. Rarely, bleeding may occur, so care should be taken if bleeding symptoms appear. Gastrointestinal disturbances such as diarrhea, nausea, abdominal pain, appetite loss, and heartburn may occur. Monitoring for changes in liver function is necessary, as liver abnormalities may develop. Symptoms of cardiovascular abnormalities, such as palpitations or hypotension, have also been reported. Various side effects may occur, including headaches, dizziness, facial flushing, tremors, swelling, etc.; if abnormal symptoms occur, consult healthcare professionals. Patients with lumbar spinal canal stenosis should determine the continuation of use based on changes in symptoms, and effectiveness in severe cases is not certain. Safety during pregnancy has not been confirmed, and uterine contractions were reported in animal studies, making it safer to avoid use in pregnant women. Safety in children has not been established, so it is advisable not to use it in young children. Elderly patients may have decreased body function, so dosage adjustment may be necessary. Additionally, administration of a large amount to healthy adults may cause transient drops in blood pressure, so caution is needed.

• Rash
• itching
• bleeding
• diarrhea
• nausea
• abdominal discomfort
• abdominal pain
• loss of appetite
• heartburn
• vomiting

This medication should be stored in a tightly closed container to prevent air or moisture from entering. It is also safe to store the medication at room temperature, which should be neither too hot nor too cold, specifically between 1°C and 30°C.

Appearance

White round tablet

Package unit

84 tablets/box [(21 tablets/Alu-Alu*4)]