HyalS Injection (Sodium Hyaluronate)

Adult dosage

Typically, for adults, administer 1 vial once a week for 3 consecutive weeks into the knee joint cavity or shoulder joint (shoulder joint cavity, subacromial bursa, or biceps brachii tendon sheath), adjusting the frequency of administration as appropriate based on symptoms.

This medication is injected into the joint cavity as it contains sodium hyaluronate. First, it should not be used in patients who have previously experienced an allergic reaction to this medication. Additionally, it must be administered with caution in patients allergic to other medications or those with liver function issues or a history of liver disease. Care should also be taken if there are skin diseases or infections at the injection site. Serious allergic reactions such as shock may occur when using this medication, so administration should be stopped immediately if symptoms appear, and appropriate treatment should be received. Other allergic symptoms such as swelling of the face or around the eyes, rashes, hives, and itching may also occur, so caution is advised. Temporary pain, swelling, warmth, and tenderness may occur at the injection site, along with symptoms such as nausea, vomiting, and fever. If administered to an inflamed joint, symptoms may worsen, so it is advisable to reduce the inflammation first before use. After administration, stabilize the injection site and ensure the medication does not leak out of the joint cavity. Injections should be performed under sterile conditions, and if symptoms do not improve, administration should be limited to three times and then stopped. If there is liquid accumulation in the joint, it should be removed prior to injection. This medication is not suitable for intravenous injection or for use in the eyes. Women who are pregnant or may become pregnant should carefully consider the therapeutic effects and risks before using this medication, and nursing mothers are advised to avoid administration. Safety has not been established for children, so it should only be administered with caution when necessary. Elderly patients may have decreased physical function, requiring more careful use.

Serious side effects

• Hives, swelling (face, eyelids, etc.) → severe allergic reactions
• Shock symptoms (unknown frequency) → severe allergic reactions

Mild side effects

• Facial swelling
• facial flushing
• rash
• itching
• pain at the injection site
• swelling
• edema
• redness
• warmth
• local tenderness

This medication should be stored in a sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius to preserve the efficacy and safety of the medication.

Appearance

A colorless, transparent, and viscous liquid contained in a glass vial sealed with rubber stoppers (part of a prefilled syringe system)

Package unit

2ml x 1 vial, 2ml x 3 vials