Wimezol 40 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids such as water and must not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: Administer 40 mg once daily for 4 weeks. If esophagitis is unresolved or symptoms continue, take for an additional 4 weeks. - Long-term maintenance therapy to prevent relapse in patients with esophagitis: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 20 mg once daily. If symptoms are not controlled after 4 weeks, further medical attention is needed. - Once symptoms improve, continue to manage recurring symptoms with 20 mg once daily. - In adults, 20 mg may be administered as needed once daily. Continuous dosing is not recommended for patients at high risk of gastric ulcers and duodenal ulcers due to nonsteroidal anti-inflammatory drug use.

Children's dosage

Adolescents over 12 years old 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: Administer 40 mg once daily for 4 weeks. If symptoms persist or are unresolved, take for an additional 4 weeks.

This drug should not be administered to certain patients. It should not be used in patients with a known allergy or hypersensitivity to this drug, its components, or similar medications. Additionally, patients taking certain antibiotics or antiviral medications, those with a history of heart disease, and breastfeeding women should refrain from using this drug. Caution is necessary as various side effects may occur while taking this medication. Reported issues include blood-related problems, allergic reactions, electrolyte imbalances, mental symptoms, gastrointestinal symptoms, liver function abnormalities, and skin reactions. Symptoms like muscle pain or weakness may indicate severe muscle damage, necessitating immediate consultation with a physician. Long-term use of this medication may mask symptoms of malignant tumors, so if there are unusual symptoms like weight loss or vomiting, it is essential to discuss them with a physician. Regular health check-ups are important for long-term users. Also, this drug can reduce stomach acid, potentially increasing bacterial count in the gastrointestinal tract, raising the risk of infections, thus inform healthcare providers if diarrhea persists. Patients with osteoporosis or those at risk of fractures should be cautious, as long-term use may increase the risk of fractures. This drug may interact with other medications, so inform healthcare providers about all medications being taken, especially when combined with anticoagulants, antibiotics, and antivirals. Safety data on this drug during pregnancy is limited, so pregnant women should only use it after consulting a physician. Breastfeeding women should avoid this drug due to the possibility of it being transmitted through breast milk. There is no specific antidote for overdose, so appropriate treatment should be sought according to symptoms, and it should be stored out of the reach of children. Additionally, this drug should be stored in its original container to maintain its quality and not transferred to another container.

Serious side effects

Urticaria, angioedema, anaphylactic reaction, shock, hypomagnesemia, mental confusion, pancreatitis, jaundice, liver failure, encephalopathy, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), muscle weakness, interstitial nephritis, Clostridium difficile-associated diarrhea, severe skin adverse reactions.

Mild side effects

• Headache
• dizziness
• sensory disturbances
• drowsiness
• taste disorder
• blurred vision
• bronchospasm
• abdominal pain
• constipation
• diarrhea

This medication can be sensitive to air and moisture, so it must be stored in a sealed container. It is also important to maintain a temperature between 1°C and 30°C when storing the medication. This way, the medication can retain its effectiveness for a longer period.

Appearance

Pink round film-coated tablet

Package unit

28 tablets/ptp [14 tablets/PTP X 2]