Medication info

Hyalto Plus Injection (Sodium Hyaluronate)

Prescription medication주사
Ingredient · strength
Sodium Hyaluronate›10mg / 1mL
Manufacturer / importer
코스맥스파마(주)
Appearance
A colorless, transparent, and viscous liquid contained in a glass or plastic tube sealed with rubber stoppers (part of a pre-filled syringe system)
Packaging
2 milliliters/pre-filled syringe (2ml x 3 syringes)
Approval status
Active

MFDS item code 201901518 · Notified 2019.03.12 · Insurance code 055100931

Summary

Main use
Relief of symptoms of knee osteoarthritis and adhesive capsulitis of the shoulder
Who receives it
Adults
Adult administration
Typically, 1 syringe is administered once a week for 3 consecutive weeks into the knee joint or shoulder joint (shoulder joint space, subacromial bursa, or tendon sheath of the biceps brachii), but the frequency of administration should be adjusted according to symptoms. This drug is administered intra-articularly, so it must be performed under strict aseptic conditions.

Ingredients

Manufacturer
코스맥스파마(주)

Efficacy & effects

Relief of symptoms of knee osteoarthritis and adhesive capsulitis of the shoulder

  • Knee osteoarthritis
  • adhesive capsulitis of the shoulder
View approved original text

This drug is used for the treatment of knee osteoarthritis and adhesive capsulitis of the shoulder.

How it is given

Adult administration

Typically, 1 syringe is administered once a week for 3 consecutive weeks into the knee joint or shoulder joint (shoulder joint space, subacromial bursa, or tendon sheath of the biceps brachii), but the frequency of administration should be adjusted according to symptoms. This drug is administered intra-articularly, so it must be performed under strict aseptic conditions.

Precautions

This drug is an injection that helps relieve intra-articular inflammation and provides lubrication through sodium hyaluronate. It should not be used in patients who have had allergic reactions to any of the ingredients contained in this drug. Patients who are allergic to other medications or have liver function issues should use this drug with more caution. Additionally, it is important to check and treat any skin diseases or infections at the injection site before administering this drug. After receiving the injection, there may be allergic reactions such as swelling of the face or around the eyes, rash, or itching, and if these symptoms occur, the administration should be stopped immediately. Temporary pain, swelling, redness, or warmth may appear at the injected joint site, so careful observation is required after administration. Rarely, systemic symptoms such as nausea, vomiting, or fever may occur. In cases of severe inflammation in the joint, this drug may worsen inflammation, so it is advisable to relieve inflammation first before using it. After injection, care should be taken to stabilize the joint area and avoid overexertion. During injection, maintain a sterile environment to reduce the risk of infection and ensure the drug does not leak outside of the joint space. This drug is not intended for intravenous injection or ophthalmic use, and a needle gauge of 22-23 is appropriate. Also, it should not be used in conjunction with certain disinfectants, as this may cause drug precipitation. Women who are pregnant or may become pregnant should only use this drug after carefully considering the need for treatment and the associated risks, as its safety has not been established. Nursing mothers should avoid breastfeeding during treatment, as this drug may be transmitted through breast milk. The safety of this drug in children has not been sufficiently confirmed, so it should only be used carefully in cases where necessary. Elderly patients may have decreased physical function, so special caution should be exercised when using this drug.

Side effects and when to seek care immediately

Serious side effects

Shock symptoms

Mild side effects

  • Swelling (facial, eyelid, etc.)
  • facial flushing
  • rash
  • urticaria
  • itching
  • pain
  • swelling
  • redness
  • warmth
  • severe localized pressure sensation
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  • nausea
  • vomiting
  • fever

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a sealed container to prevent air or moisture from entering, and it is important to store it at a controlled temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the effectiveness of the drug for a longer period.

Appearance and packaging

Appearance

A colorless, transparent, and viscous liquid contained in a glass or plastic tube sealed with rubber stoppers (part of a pre-filled syringe system)

Package unit

2 milliliters/pre-filled syringe (2ml x 3 syringes)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.