Medication info
Altisan Tablets 480 mg (R-Tocopherol-Trimethamine Salt)

Altisan Tablets 480 mg (R-Tocopherol-Trimethamine Salt)

Prescription medicationTabletOral
Ingredient · strength
R-Thioctic Acid Tromethamine›480mg / 1 tablet
Manufacturer / importer
Daewoo Pharmaceutical Co., Ltd.
Appearance
Light green oblong film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201901499 · Approved 2019.03.12

Summary

Main use
Relief of diabetic polyneuritis
Who takes it
Adults
Adult dose
Adults: Take 480 milligrams of thioctic acid tromethamine once daily with plenty of water, approximately 30 minutes before breakfast.

Ingredients

Manufacturer
Daewoo Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of diabetic polyneuritis

  • Diabetic polyneuropathy
View approved original text

This medication is used to relieve symptoms caused by diabetic polyneuropathy.

How to take

Adult dose

Adults: Take 480 milligrams of thioctic acid tromethamine once daily with plenty of water, approximately 30 minutes before breakfast.

Precautions

This medication contains R-Tocopherol-Trimethamine Salt, and should not be used by individuals who are allergic to this ingredient or similar drugs. This drug contains Yellow No. 4, and caution should be exercised by those who have allergic reactions or hypersensitivity to this component. During use, side effects such as sensory disturbances, headache, constipation, dry mouth, cough, cystitis, diarrhea, and other complications may occur, and serious adverse reactions such as kidney stones or facial swelling have been reported in some patients. Additionally, this medication is mainly used for patients with diabetic neuropathy, and regular alcohol consumption may decrease the drug's efficacy, so it is advisable to avoid alcohol intake. There may be interactions with other medications; particularly, if taken with iron or magnesium preparations, or milk, absorption may be hindered, so dosing times should be adjusted. Furthermore, when used concurrently with insulin or other diabetes medications, there may be a risk of low blood sugar, so blood sugar levels should be monitored frequently, and dosage adjustments may be necessary. The safety of this drug has not been fully established in pregnant or breastfeeding women; hence, it should only be used after consulting with a physician. There is no experience with the use of this drug in children under 18, so it is advisable not to use it in this age group. In case of an overdose, serious intoxication symptoms may occur, and it is essential to go to a hospital immediately for appropriate treatment. This medication should be stored in a sealed container to prevent air or moisture entry and should be kept at room temperature between 1 to 30 degrees Celsius, away from excessive heat or extreme cold.

Side effects

  • paresthesia
  • pain
  • sensory loss
  • headache
  • constipation
  • abdominal discomfort
  • nasopharyngitis
  • dry mouth
  • cough
  • cystitis
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  • diarrhea
  • burning sensation
  • nephrolithiasis
  • lumbar canal stenosis
  • facial swelling
  • dry mouth
  • myalgia
  • nausea
  • decreased appetite
  • arthralgia
  • palpitations
  • insomnia
  • upper limb fracture
  • hypoglycemia
  • neurogenic bladder
  • diabetic retinopathy
  • colitis
  • benign gastric neoplasm
  • gastrointestinal bleeding
  • exacerbation of disease
  • soft tissue infection
  • cold
  • body aches
  • plantar fasciitis
  • herniated disc
  • thyroiditis
  • increased LDH
  • increased triglycerides
  • weight loss
  • abnormal blood sugar
  • shingles
  • dysuria
  • worsening of kidney function
  • vaginitis
  • conjunctivitis
  • floaters
  • unspecified retinal vascular disorder
  • heart palpitations
  • acute abdominal symptoms
  • colon polyp
  • benign oral neoplasm
  • benign gastrointestinal neoplasm
  • gastroesophageal reflux disease
  • gastritis
  • gastroenteritis
  • cavities
  • periodontitis
  • rectal bleeding
  • chest pain
  • peripheral edema
  • edema
  • limb pain
  • carpal tunnel syndrome
  • flank pain
  • generalized edema
  • general weakness
  • back pain
  • sleep disorder
  • simple partial seizure
  • facial paralysis
  • bitter taste
  • genital pruritus
  • nail changes
  • blisters
  • dermatitis
  • unspecified peripheral vascular disease
  • gum bleeding
  • sputum disease
  • bronchitis
  • throat infection
  • sinusitis
  • congestion
  • upper respiratory infection
  • allergic atopic rhinitis
  • dyspnea
  • nausea
  • vomiting
  • gastrointestinal pain
  • skin rash
  • hives
  • itching
  • dizziness
  • sweating
  • taste disorder
  • epigastric pain
  • dyspepsia
  • pruritus
  • abdominal pain
  • heartburn
  • restlessness
  • altered consciousness
  • generalized seizures
  • lactic acidosis
  • shock
  • rhabdomyolysis
  • hemolysis
  • disseminated intravascular coagulation
  • bone marrow suppression
  • multiple organ failure

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air or moisture entry. Additionally, it is best to store the medication at room temperature between 1 to 30 degrees Celsius, away from excessive heat or cold.

Appearance and packaging

Appearance

Light green oblong film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.