Donepezil Hydrochloride 10 mg Tablets

Adult dose

As donepezil hydrochloride, take 5 mg once daily before bedtime. If unusual dreams, nightmares, or insomnia occur, morning dosing of this medication may be considered. Donepezil concentration reaches a steady state 15 days after administration, and the frequency of adverse reactions may be affected by the rate of dose escalation, hence a dose of 5 mg should be administered for 4 to 6 weeks. During this period, clinical responses will be evaluated.

Child dose

No experience of use in children.

This drug contains donepezil hydrochloride as its main ingredient and is used for the treatment of Alzheimer's dementia symptoms. This drug should not be administered to certain patients, such as those with allergies to this drug or its components, pregnant women or women who may become pregnant, nursing mothers, and patients with genetic issues like lactose intolerance. Patients with heart disease, a history of peptic ulcers, those taking non-steroidal anti-inflammatory drugs, asthma or obstructive pulmonary disease, and those with extrapyramidal disorders such as Parkinson's disease should use this medication cautiously. This drug may slow heart rate or cause arrhythmias, so the cardiac health status should be closely monitored. Additionally, it may increase gastric acid secretion and promote gastrointestinal motility, worsening peptic ulcers, hence attention to gastrointestinal symptoms is necessary. During medication use, side effects such as nausea, vomiting, diarrhea, dizziness, insomnia, muscle pain, and fatigue may occur, and in severe cases, fainting, heart problems, liver dysfunction, cerebrovascular anomalies, and movement disorders may arise. This medication may affect driving ability or machinery operation, so caution is needed at the beginning of treatment or when the dosage is changed. Pregnant or nursing women are advised not to use this medication unless absolutely necessary, and should consult a professional before use. This medication can interact with other drugs, especially caution is needed when used in combination with heart-related drugs, antibiotics, antidepressants, and antipsychotic medications. In case of overdose, symptoms such as nausea, vomiting, bradycardia, hypotension, and seizures may appear, and immediate medical attention should be sought for proper treatment. Finally, this medication should be stored out of the reach of children, and transferring it to other containers should be avoided.

Serious side effects

Fainting, bradycardia, heart block, prolonged QT interval, myocardial infarction, heart failure, peptic ulcer, perforated duodenal ulcer, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, seizures, brain hemorrhage, cerebrovascular disorders, extrapyramidal disorders (movement dysfunction, ataxia, movement disorders, dystonia, tremor, involuntary movements, gait disturbance, abnormal posture, speech disorders), malignant neuroleptic syndrome (stupor, extreme muscle rigidity, dysphagia

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• drowsiness
• insomnia
• dizziness
• tremor

This medication should be stored in an airtight, sealed container at a temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain the drug's effectiveness and prevents degradation.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle