Medication info

Erovatin Tablets 5/20 Milligrams

Prescription medicationTablet경구Expired
Ingredient · strength
Atorvastatin Calcium›20.72mg / 1 tabletAmlodipine Besylate›6.94mg / 1 tablet
Manufacturer / importer
메딕스제약(주)
Appearance
White oval film-coated tablets
Packaging
30 tablets/bottle
Approval status
Expired

MFDS item code 201901323 · Approved 2019.03.04

This product's status changed to Expired on 2024.03.04. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
(Hypertension, Angina) Reducing cardiovascular risk and improving dyslipidemia
Who takes it
Adults
Adult dose
This medication is administered only to adults, and the dosage should be individualized for each patient based on the efficacy and tolerability of amlodipine/atorvastatin. Amlodipine (Escitalopram Amlodipine): Administer 5 (2.5) mg orally once daily, with a maximum increase of up to 10 (5) mg daily based on patient's response. Atorvastatin: The recommended initial dose is 10 mg once daily, and if needed, it can be increased to 20 mg or 40 mg.

Ingredients

Manufacturer
메딕스제약(주)

Efficacy & effects

(Hypertension, Angina) Reducing cardiovascular risk and improving dyslipidemia

  • Hypertension
  • fixed occlusion of coronary arteries
  • vasospasm of the coronary circulation
  • vascular contraction
  • myocardial ischemia
  • angina
  • heart failure
  • reduced cardiac output
  • coronary heart disease
  • myocardial infarction
  • stroke
  • revascularization
View approved original text

This medication is used for patients with hypertension or coronary artery disease who need to take both amlodipine and atorvastatin simultaneously. Amlodipine works by dilating blood vessels to improve hypertension and stable angina, as well as ischemia caused by variant angina. It also reduces the risk of hospitalization for angina in patients without heart failure and normal cardiac output, as well as the need for coronary revascularization. Atorvastatin lowers the risk of cardiovascular diseases like myocardial infarction, stroke, and angina, while improving serum cholesterol and triglyceride levels, thus aiding in the treatment of dyslipidemia. Additionally, it reduces the risk of revascularization and decreases the hospitalization risk due to congestive heart failure. In summary, this medication is effective for the prevention and treatment of hypertension and various cardiovascular diseases, and is used to improve serum lipid levels.

How to take

Adult dose

This medication is administered only to adults, and the dosage should be individualized for each patient based on the efficacy and tolerability of amlodipine/atorvastatin. Amlodipine (Escitalopram Amlodipine): Administer 5 (2.5) mg orally once daily, with a maximum increase of up to 10 (5) mg daily based on patient's response. Atorvastatin: The recommended initial dose is 10 mg once daily, and if needed, it can be increased to 20 mg or 40 mg.

Precautions

This medication should not be used in certain patients. For example, it should not be administered to patients with allergies to this medication or similar substances, severe liver dysfunction, pregnant or potentially pregnant women, nursing mothers, patients with severe muscle disease, those suffering severe aortic stenosis, patients in a state of shock, patients within one month after myocardial infarction, and those with unstable angina. Furthermore, patients with severely impaired renal function, the elderly, individuals with a history of alcohol dependence or liver disease, and those at risk of muscle diseases should use this medication with caution. This medication is generally well-tolerated; however, mild to moderate side effects such as facial flushing, fatigue, edema, dizziness, headache, and dyspepsia may occur. Rarely, muscle pain, liver function abnormalities, and allergic reactions have also been reported. Women who are pregnant or may become pregnant should not use this medication, and nursing mothers should stop breastfeeding if on this medication. This medication may interact with various other drugs; therefore, patients taking other medications must inform their physician or pharmacist. Care should especially be taken when used concomitantly with certain antibiotics, antifungals, immunosuppressants, or specific antiviral drugs. The impact on driving or machinery operation is minimal; however, caution is advised as symptoms like dizziness may occur. In case of overdose, severe hypotension, tachycardia, or shock may occur, requiring immediate medical attention and intervention. The safety and efficacy of this medication in children and the elderly have not been sufficiently established, thus it should be used with caution in these age groups. Lastly, this medication should be kept out of reach of children, and transferring it to another container should be avoided as it could adversely affect quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, severe allergic reactions, severe rash accompanied by fever, blisters, skin peeling, pain in mucosal membranes of mouth/eyes, severe cutaneous adverse reactions, difficulty in breathing or shortness of breath, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and severe headache, thunderclap headache, seizures, altered consciousness

Mild side effects

  • Flushing
  • fatigue
  • edema
  • palpitations
  • dizziness
  • headache
  • drowsiness
  • abdominal pain
  • nausea
  • weakness
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  • lethargy
  • pain
  • weight gain/loss
  • hypotension
  • vasculitis
  • muscle spasms
  • sensory loss/parethesia
  • peripheral neuropathy
  • syncope
  • altered taste
  • tremors
  • extrapyramidal symptoms
  • erectile dysfunction
  • gynecomastia
  • changes in bowel habits
  • dry mouth
  • dyspepsia
  • gingival hyperplasia
  • gingival proliferation
  • pancreatitis
  • vomiting
  • hyperglycemia
  • arthralgia
  • low back pain
  • muscle cramps

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is best stored at room temperature between 15 to 30 degrees Celsius, avoiding extreme heat or cold.

Appearance and packaging

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.