Medication info

Tyrokae Injection (Tyropamide Hydrochloride)

Prescription medicationInjectionsIntravenous injectionApproval withdrawn
Ingredient · strength
Tiropramide Hydrochloride›50mg / 1 ampoule
Manufacturer / importer
Genewon Science Co., Ltd.
Appearance
A colorless transparent liquid in a brown ampoule injection
Packaging
3mL x 1 ampoule, 50 ampoules ((3mL/ampoule)x50EA)
Approval status
Approval withdrawn

MFDS item code 201901296 · Approved 2019.02.28

This product's status changed to Approval withdrawn on 2024.01.10. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Relief of acute spasmodic pain (such as abdominal and hepatobiliary colic), abdominal spasms, and pain
Who receives it
Adults
Adult administration
Adults: Administer 50㎎(3㎖) of tiropamide hydrochloride by intramuscular or intravenous injection. The dose may be repeated after 1 hour if needed. Adjust the dose appropriately according to age and symptoms.

Ingredients

Manufacturer
Genewon Science Co., Ltd.

Efficacy & effects

Relief of acute spasmodic pain (such as abdominal and hepatobiliary colic), abdominal spasms, and pain

  • Acute colicky pain
  • biliary colic
  • abdominal pain
  • renal colic
  • ureteral colic
  • abdominal cramps
  • pain
View approved original text

This medication is used to relieve acute colicky pain such as biliary colic, abdominal pain caused by various reasons, and renal and ureteral colic. It is also effective in treating abdominal cramps and pain due to gastrointestinal dysmotility, cholelithiasis, cholecystitis, and postoperative adhesions. This medicine helps to reduce abdominal colicky pain and improve patient discomfort.

How it is given

Adult administration

Adults: Administer 50㎎(3㎖) of tiropamide hydrochloride by intramuscular or intravenous injection. The dose may be repeated after 1 hour if needed. Adjust the dose appropriately according to age and symptoms.

Precautions

This drug should not be used in patients with narrowed gastrointestinal tracts. Also, it should not be used in patients with abnormally enlarged intestines or impaired function. Patients who are allergic to this drug must avoid it. Patients with severely impaired liver function should not take this medication. Although this drug does not have anticholinergic effects in patients with glaucoma or prostatic hyperplasia, it should still be used cautiously. Taking this drug may cause symptoms such as dry mouth, nausea, vomiting, and constipation. If an allergic reaction such as itching or rash occurs, use should be discontinued immediately. Patients taking blood pressure lowering medications should be cautious with high doses of this drug, as blood pressure may become too low. Pregnant women should only use this drug under the supervision of a physician when absolutely necessary, as animal studies have shown no significant problems. When administered intravenously, it should be slowly infused into patients with low blood pressure for safety. Finally, caution should be exercised when opening this drug's ampoule, as glass fragments may occur; especially when used by children or the elderly, care should be taken to cut it carefully.

Side effects

  • dry mouth
  • nausea
  • vomiting
  • constipation
  • itching
  • erythema

Not everyone experiences these, and they can vary from person to person.

Storage

This drug is sensitive to light and should be stored in a tightly closed container that blocks light. Additionally, the product should be stored at room temperature, ideally maintaining a temperature between 1 degrees and 30 degrees. This will help to preserve the drug's efficacy and safety.

Appearance and packaging

Appearance

A colorless transparent liquid in a brown ampoule injection

Package unit

3mL x 1 ampoule, 50 ampoules ((3mL/ampoule)x50EA)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.