Ezetu Tablets (Ezetimibe)

Adult dosage

The recommended dosage of this medication is 10 mg once daily, regardless of meals. When used in combination with HMG-CoA reductase inhibitors, it should be started at the recommended initial dose of the HMG-CoA reductase inhibitor together with this medication, and for patients already taking high doses of the HMG-CoA reductase inhibitor, the dosage of the HMG-CoA reductase inhibitor should be maintained while adding this medication.

This medication should not be used in patients who are allergic to certain components. Patients with liver dysfunction or persistently abnormal liver enzyme levels should not take this medication with other specific lipid-lowering agents. Women who are pregnant or nursing are prohibited from combining this medication with certain lipid-lowering agents, so consultation with a physician is necessary if required. The use of this medication is not recommended in patients with moderately or severely impaired liver function, and liver function should be monitored periodically. During treatment with this medication, side effects such as headache, abdominal pain, diarrhea, and fatigue may occur; if these symptoms persist or worsen, consult a physician. If symptoms of muscle pain or weakness arise, notify medical personnel immediately, and in severe cases, discontinuation of the medication may be necessary. Patients with impaired kidney function may take this medication, but caution is required when used in combination with other medications, and physician’s guidance should be followed. As there may be interactions with other medications, it is important to inform the healthcare provider of any current medications. Pregnant or nursing women should consider the potential risks of this medication before deciding to administer it, and women of childbearing potential should take care with contraception. The drug is not recommended for children under 6 years of age; from age 6 and above, it may be administered at the discretion of a physician. Older adults may also use this medication, but careful observation is needed due to possible differences in sensitivity with age. In case of overdose, seek medical attention immediately for appropriate treatment, and symptomatic relief measures may be necessary. Keep the medication out of reach of children and do not transfer it to another container for safety.

Serious side effects

Hives, severe swelling (edema), angioedema, anaphylaxis, hypersensitivity reactions, erythema multiforme, persistent elevation of aminotransferase levels (liver dysfunction), hepatitis, pancreatitis, thrombocytopenia, cholelithiasis, cholecystitis, gallbladder-related adverse reactions, rhabdomyolysis, myopathy, muscle weakness, severe edema, kidney failure, kidney injury, heart-related chest pain, cardiovascular issues (congestive heart failure, myocardial ischemia).

Mild side effects

• Fatigue
• abdominal pain
• diarrhea
• viral infection
• pharyngitis
• sinusitis
• joint pain
• back pain
• cough
• chest pain

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. It should be kept at a temperature between 1 and 30 degrees Celsius to maintain its effectiveness.

Appearance

White to almost white rectangular tablets

Package unit

30 tablets (10 tablets/PTP x 3)