Albion Tablets

Adult dose

Typically, administer 2 tablets orally twice a day at morning and bedtime, without regard to meals. 1) Gastric and duodenal ulcers: 2 tablets twice a day or 4 tablets once a day at bedtime. Particularly for patients with duodenal ulcers, administering 4 tablets twice a day at morning and bedtime can yield a higher therapeutic rate. The dosage for preventing ulcers induced by non-steroidal anti-inflammatory drugs or during long-term NSAID therapy is the same. Typically, diseases induced by non-steroidal anti-inflammatory drugs are healed within 8 weeks, but healing durations may occasionally extend depending on the patient. For recurrent ulcer patients where short-term therapy has been effective, maintain therapy by administering 2 tablets once a day at bedtime. 2) Gastroesophageal reflux disease: For 8 weeks, administer 2 tablets twice a day or 4 tablets once a day at bedtime. For severe gastroesophageal reflux disease patients, the dosage may be increased to 4 tablets four times a day. 3) Zollinger-Ellison syndrome: Start treatment with an initial dose of 2 tablets three times a day, and adjust as needed. In severe cases, the daily dose of ranitidine may be increased up to 6g as directed by a physician. 4) Peptic ulcer, acute stress ulcers, and upper gastrointestinal bleeding due to acute mucosal lesions: Once oral administration is possible, transition from injection to oral dosing of 2 tablets twice a day. 5) Pre-anesthetic dosage (prevention of Mendelson syndrome): Administer 2 tablets 2 hours before anesthesia induction. It is also advisable to administer 2 tablets the night before surgery.

This medication should not be used in patients undergoing dialysis or those who have had allergic reactions to this medication or its components. It is also unsafe to administer to patients with a history of acute porphyria, those with poor kidney function, surgical patients, pregnant women or those who may become pregnant, premature infants and newborns, and patients on potassium-restricted diets. Caution is advised when using in patients with impaired liver function, a history of drug allergies, the elderly, patients with kidney issues, and those taking non-steroidal anti-inflammatory drugs concurrently. Particularly, it can conceal symptoms of gastric cancer; thus, in middle-aged or older patients who recently developed or changed indigestion symptoms, confirm that it is not a malignant disease before administering. Patients with helicobacter pylori infection and gastric/duodenal ulcers should undergo bacterial eradication treatment as well. Serious patients in intensive care or those with hypophosphatemia and patients who have difficulty swallowing should be monitored closely. While taking this medication, allergic reactions such as skin rashes, urticaria, angioedema, breathlessness, hypotension may occur, thus if such symptoms arise, immediately discontinue the medication and consult a physician. Rarely, blood tests may show decreased white blood cells or platelets, so if symptoms like fatigue, bleeding, or fever occur, tests should be conducted and medications stopped if necessary. If symptoms of liver dysfunction or jaundice appear, discontinue the medication immediately. There may be irregular heart rhythms, so caution is needed if there are symptoms like dizziness or heart-related issues. Gastrointestinal symptoms may include nausea, vomiting, constipation, diarrhea, and abdominal pain; stools may darken, but this does not require special treatment. In severe patients or the elderly, neurological issues like confusion, drowsiness, headaches, insomnia, and hallucinations may occur, necessitating careful observation. Muscle pain or joint pain may occur, and in rare cases, serious muscle damage symptoms have been reported; if any abnormal symptoms arise, discontinue the medication. Skin rashes or hair loss may occur infrequently. This medication should not be used for long periods, and if there is no therapeutic effect, it is advisable to switch to another medication. Elderly patients or those with chronic lung disease, diabetes, and immunocompromised conditions may have increased risk for pneumonia, necessitating caution. If dizziness or drowsiness occurs, avoid driving or operating hazardous machinery. This medication may interact with other medications, so if taking other drugs, inform your physician or pharmacist, especially if taking medications that affect blood coagulation, as frequent blood tests may be required. It is safest for pregnant women or those who may become pregnant, and lactating mothers to refrain from using this medication. Safety and efficacy have not been fully established for children, so it is advisable not to use it in this population. In case of overdose, treatments such as vomiting or gastric lavage may be necessary, and in severe cases, blood dialysis may help. This medication can reduce gastric acid secretion, promoting bacterial growth in the stomach, thus regular examinations, including eye tests, may be needed with long-term use.

Serious side effects

• Urticaria, severe swelling (angioedema), chest tightness, breathing difficulty, cold sweat, pallor → severe allergic reaction.
• High fever with severe rash, blisters, peeling skin, pain in oral/ocular mucosa → severe skin adverse reactions.
• Shortness of breath or difficulty breathing, asthma attacks, cough with fever → respiratory issues.
• Skin or eyes turning yellow (jaundice), extreme lethargy → liver abnormality (jaundice).

Mild side effects

• Skin rashes
• urticaria
• angioedema
• fever
• bronchospasm
• hypotension
• chest pain
• granulocytopenia
• leukopenia
• thrombocytopenia

This medication should be stored in a sealed container to prevent air or moisture from entering. Additionally, it is best to store it at room temperature between 1°C and 30°C. Proper storage helps to maintain the medication's effectiveness.

Appearance

This medication is a round, white film-coated tablet.

Package unit

30 tablets/bottle, 300 tablets/bottle