Barozet Tablet 10/20 mg

Adult dose

This medication is administered once a day in the evening, regardless of meals. For patients with primary hypercholesterolemia, the dosage range is 10/10 mg to 10/40 mg per day, and the generally recommended initial dose is 10/20 mg per day. Patients with less need for LDL-cholesterol reduction may start at 10/10 mg once daily. After initiation of therapy or dose adjustment, blood lipid levels should be checked after an interval of at least 4 weeks.

This medicine is used to lower cholesterol levels. However, it can cause muscle-related issues, with symptoms such as muscle pain or weakness. In particular, there is a risk of rare side effects like rhabdomyolysis, which involves severe muscle damage, so caution is required. If experiencing muscle pain, tenderness, or weakness while taking this medication, you should inform your doctor immediately. Also, this medication may affect liver function, so it is not recommended for patients with liver disease or elevated liver enzyme levels. Women who are pregnant or nursing should not take this medication, and women who may become pregnant should consult a doctor before use. The risk of muscle damage can increase when taken with certain drugs, so you must inform your doctor if you are on other medications. Caution is especially needed when used with drugs that inhibit enzymes that metabolize drugs in the liver, certain antibiotics, antiviral drugs, or immunosuppressants. Elderly patients or those with reduced kidney function also have a higher risk of muscle problems while taking this medication, necessitating careful monitoring. It is recommended to regularly check liver function and muscle condition through blood tests while using this medication. There is no specific antidote for overdose, so if overdosed, immediate medical treatment is necessary. Finally, it is advisable to avoid excessive consumption of grapefruit juice while taking this medication, as it can increase the drug's concentration in the blood and elevate the risk of side effects.

Serious side effects

Myopathy, rhabdomyolysis, increased serum creatine kinase, persistent elevation of serum aminotransferase levels, marked elevation of serum aminotransferases, liver failure, cholestatic jaundice, severe liver injury, severe allergic reactions (urticaria, angioedema, rash), toxic epidermal necrolysis (Lyell syndrome), mucosal hypersensitivity syndrome (Stevens-Johnson syndrome), severe skin adverse reactions, urticaria, facial swelling, angioedema,

Mild side effects

• Headache
• diarrhea
• influenza
• upper respiratory infection
• muscle pain
• limb pain
• weakness
• abdominal pain
• nausea
• constipation

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature to ensure the drug's effects and safety remain intact over time.

Appearance

White to pale yellow, double-convex, rectangular tablet

Package unit

30 tablets (10 tablets/PTP × 3)