Barozet Tablet 10/10 mg

Adult dose

This medication is administered once daily in the evening, regardless of meals. For patients with primary hypercholesterolemia, the dosage range is 10/10 mg to 10/40 mg daily, and the generally recommended initial dose is 10/20 mg daily. Patients with lower need for LDL cholesterol reduction may start at 10/10 mg daily. After starting treatment or adjusting the dosage, blood lipid levels should be checked after an interval of at least 4 weeks.

This medication can cause serious muscle disorders such as myopathy and rhabdomyolysis, so if muscle pain, muscle weakness, or unexplained muscle pain occurs during treatment, consult a physician immediately. This medication should not be administered to patients with specific liver diseases or poor liver function, and regular liver function tests are necessary if liver dysfunction is suspected. Women who are pregnant or breastfeeding should not use this medication, and women of childbearing potential must consult a physician before use and utilize appropriate contraception. This medication may interact with other drugs, especially medications that inhibit enzymes involved in drug metabolism in the liver, which could increase the risk of muscle damage; therefore, inform healthcare professionals of any other medications being taken. Elderly patients or those with reduced kidney function should also exercise caution when taking this medication, and dosage adjustments or regular testing is recommended. In some patients, blood sugar may rise due to this medication; thus, regular blood sugar testing is necessary for those at risk of diabetes. While taking this medication, consumption of certain foods, such as grapefruit juice, should be limited, and immediate treatment is required in case of overdose, so strictly adhere to the dosage. This medication is used restrictively in children and adolescents, particularly not recommended for children under 10 years old. If any adverse reactions or discomfort persist after administration, inform healthcare professionals immediately, and regular blood tests to monitor liver function and muscle status are important.

Serious side effects

Angioedema, severe rash, hypersensitivity reaction, pancreatitis, cholelithiasis, cholecystitis, anaphylaxis, angioedema, lupus-like erythema syndrome, polymyositis, dermatomyositis, vasculitis, purpura, thrombocytopenia, leukopenia, hemolytic anemia, positive antinuclear antibody, increased erythrocyte sedimentation rate, eosinophilia, arthritis, arthralgia, urticaria, photosensitivity, fever, chills, flushing, malaise, difficulty breathing, toxic epidermal necrolysis (Lyell’s syndrome)

Mild side effects

• Headache
• diarrhea
• influenza
• upper respiratory infection
• muscle pain
• limb pain
• fatigue
• abdominal pain
• nausea
• constipation

Store this medication in a tightly closed container that protects against air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. This helps to preserve the medication's effectiveness and prevent degradation.

Appearance

White to pale yellow, biconvex, rectangular tablet

Package unit

30 tablets (10 tablets/PTP ×3)