Celewin Capsule 100mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient. It may be administered with or without food. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg twice daily. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may pose a risk of gastrointestinal bleeding in individuals who regularly consume three or more alcoholic drinks daily; therefore, it is essential to consult a doctor or pharmacist. This medication may affect the cardiovascular system and increase the risk of serious thromboembolic events such as myocardial infarction or stroke, so it should only be used at the lowest effective dose and for the shortest duration necessary. Given the risk of developing ulcers or gastrointestinal bleeding, particular caution should be taken by those with a history of gastrointestinal diseases or elderly patients. If symptoms like epigastric pain, dyspepsia, dark stool, or hematemesis occur, immediate medical attention should be sought. Individuals with allergic reactions or specific liver, kidney, or heart diseases, pregnant or breastfeeding women, and those with certain inflammatory bowel diseases should not take this medication. Patients with liver or kidney dysfunction, asthma, hypertension, or those taking diuretics or antihypertensives should use this medication with caution and should have their condition monitored regularly. Dizziness or drowsiness may occur during treatment, so it is advisable to avoid driving or operating machinery. This medication does not affect blood coagulation; therefore, if you are taking anticoagulants, do not discontinue the medication but consult healthcare professionals. Additionally, there may be interactions with other substances, so if you are currently taking any other medications, be sure to inform your doctor or pharmacist, especially when taken with medications metabolized by the liver. Women who are pregnant or planning to become pregnant should avoid using this medication, and if pregnancy is confirmed while taking the drug, it should be discontinued immediately and healthcare professionals consulted. Elderly patients may have impaired liver and kidney functions, so dosage adjustments and regular monitoring may be necessary. If taking this medication long-term, regular blood tests and assessments of liver and kidney function should be conducted to check for abnormalities. In case of overdose, symptoms such as vomiting, drowsiness, and nausea may appear, requiring immediate treatment; visiting the emergency room is recommended. Finally, keep this medication out of the reach of children and avoid transferring it to other containers.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, flatulence, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, urinary frequency, nephrolithiasis, incontinence, urinary tract infection, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, olfactory loss, taste loss, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, angioedema, loss of appetite, increased appetite, depression, neural hyperreactivity, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infection, sinusitis, pharyngitis, rhinitis, bronchospasm, exacerbated bronchospasm, dyspnea, laryngitis, pneumonia, epistaxis, voice disorders, vesicular dermatitis, dermatitis, nail disorders, phototoxic reactions, pruritus, erythematous rash, maculopapular rash, skin dryness, increased sweating, erythema multiforme, desquamative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash, arrhythmia, left ventricular hypertrophy, angina pectoris, unstable angina, coronary artery disease, myocardial infarction, heart failure, palpitations, tachycardia, stroke, aortic valve stenosis, hematoma, sinus bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombophlebitis, vasculitis, deep vein thrombosis, cerebral hemorrhage, solitary, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic tumors, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, synovial sacs, arthralgia, arthrosis, skeletal anomalies, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, back pain, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, rosacea, contact dermatitis, injection site reactions, cutaneous nodules, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, phototoxic reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, desquamative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, microangiopathic glomerulonephritis, menstrual disorders, female infertility, chest pain, lethargy, drowsiness, nausea, upper abdominal pain, gastrointestinal bleeding, hypertension, acute renal failure, respiratory depression, coma

This medication should be stored in a tightly sealed container that prevents air exposure and kept in a cool place between 15 to 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness for a longer period.

Appearance

A white capsule filled with a white to light yellow powder with a blue stripe on the top and bottom.

Package unit

For domestic use - 30 capsules/bottle, For domestic use - 100 capsules/bottle