Dineupen Tablets (Dexibuprofen)

Adult dose

As dexibuprofen, 300 mg is taken orally 2 to 4 times a day. However, do not exceed 1,200 mg of dexibuprofen per day.

Patients who regularly consume more than 3 alcoholic beverages per day should consult a physician or pharmacist before taking this medication, as this may increase the risk of gastrointestinal bleeding. This medication may increase the risk of cardiovascular diseases, with the possibility of severe vascular conditions such as myocardial infarction or stroke. Those with a history of cardiovascular disease or risk factors should be particularly cautious and should consult healthcare professionals immediately if symptoms occur. This medication can cause serious issues such as gastrointestinal bleeding, ulcers, or perforation. Elderly patients or those taking it over an extended period may be at higher risk, so gastrointestinal symptoms should be monitored carefully. Those with a history of gastrointestinal ulcers or bleeding, severe liver, kidney, or heart disease, or allergies to this drug or its ingredients should not take it. Additionally, individuals who have had hypersensitivity reactions to aspirin or other non-steroidal anti-inflammatory drugs should avoid this medication. It is advisable not to take this drug in conjunction with aspirin, other anti-inflammatory medications, or high-dose methotrexate, as co-administration may increase the risk of side effects. Avoid breastfeeding while taking this medication. Dizziness or fatigue may occur, and caution should be exercised when driving or operating machinery. Prolonged high-dose use may cause headaches. Individuals with blood disorders, liver impairment, kidney impairment, high blood pressure, heart failure, the elderly, and pregnant women should consult healthcare professionals before taking this medication. Consultation with an expert is also necessary for those taking multiple medications due to the potential for drug interactions. If serious side effects such as shock, severe skin rashes, gastrointestinal bleeding, liver dysfunction, kidney dysfunction, cardiovascular issues, or neurological symptoms occur while taking this medication, it should be discontinued immediately, and medical advice should be sought. This medication should be used at the minimal effective dose and for the shortest duration needed. Long-term use requires regular blood tests and monitoring of liver and kidney function. Moreover, this medication is a symptomatic treatment and does not cure the underlying cause. After 20 weeks of pregnancy, caution is necessary as it may affect fetal kidney function, and immediate medical attention is required in the event of overdose. Store this medication in a sealed container to prevent exposure to air or moisture, in a cool and dry place away from direct sunlight, and avoid transferring it to another container.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rashes with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), profound lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination abnormalities

Mild side effects

• Dyspepsia
• itching
• restlessness
• facial swelling
• diarrhea
• vomiting
• dizziness
• fatigue
• drowsiness
• anxiety

Drug interactions

Do not use this medication with other non-steroidal anti-inflammatory drugs or aspirin. Additionally, avoid using corticosteroids, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, ACE inhibitors or angiotensin II receptor antagonists, diuretics, lithium, coumarin anticoagulants, baclofen, immunosuppressants (cyclosporine, tacrolimus, sirolimus), thrombolytics, ticlopidine, antithrombotics, and potassium-raising agents.

Food interactions

Caution is needed when taking this medication with alcohol.

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, at room temperature between 1 degree and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness for a longer duration.

Appearance

White rectangular film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle