Orlistat Capsule 60 mg (Orlistat)

Adult dose

○ Adults The recommended dose is 120mg of orlistat orally 3 times daily, taken with a fat-containing meal or within 1 hour after a meal. Patients should continue to follow a nutritionally balanced, mildly hypocaloric diet in which approximately 30% of calories are derived from fat. Daily intake of fat, carbohydrates, and protein should be distributed evenly among the three meals. This medicine may be omitted if a meal is missed or contains no fat. Because this medicine may reduce the absorption of some fat-soluble vitamins and beta-carotene, patients are advised to take a multivitamin containing fat-soluble vitamins to ensure adequate nutrition. The vitamin supplement should be taken at least 2 hours before this medicine or at least 2 hours after it, such as at bedtime. Taking more than 120mg per dose 3 times daily does not increase the efficacy of this medicine. Based on measurements of fecal fat, the effect of this medicine appears 24 ∼ 48 hours after dosing. After discontinuation, fecal fat content generally returns to pretreatment levels within 48 ∼ 72 hours. The efficacy and safety of this medicine have not been evaluated for periods exceeding 4 years. No studies have been conducted in patients with hepatic and/or renal impairment or in older adults.

Child dose

No studies have been conducted in children under 12 years of age.

This medication should not be used in patients with chronic malabsorption syndrome or cholestasis. Individuals who are allergic to this medication or its components should also avoid taking it. Pregnant women, women who may become pregnant, and breastfeeding women should not take this medication. Patients with liver function issues should use this medication with caution, and they must inform their doctor and stop taking the medication if symptoms of liver impairment occur. Furthermore, caution is required in patients with hyperoxaluria or calcium oxalate nephrolithiasis due to increased urinary oxalate excretion. Taking this medication may frequently result in gastrointestinal symptoms, such as abdominal pain, changes in bowel habits, fatty stools, oily discharge, increased bowel movements, fecal incontinence, oily stools, nausea, vomiting, upper respiratory infections, lower respiratory infections, influenza, headache, sleep disturbances, fatigue, rash, dry skin, menstrual irregularities, vaginitis, urinary tract infections, anxiety, depression, ear infections, swelling of the feet, abdominal pain, leg pain, arthritis, muscle pain, joint pain, and tendinitis. When taken with a high-fat meal, this medication may increase gastrointestinal side effects, so it is recommended to distribute fat intake evenly across three meals daily. Additionally, this medication can interfere with the absorption of fat-soluble vitamins, so it is advisable to take multivitamin supplements containing vitamins A, D, E, K, and beta-carotene. Vitamin supplements should be taken at least two hours before or after taking this medication. If symptoms of liver dysfunction (decreased appetite, itching, jaundice, changes in urine color, changes in stool color, right upper abdominal pain) occur, immediate medical attention is required, and liver function tests should be conducted. This medication may affect blood sugar control in diabetic patients, so monitoring blood glucose and adjusting medication dosage may be necessary. Excessive weight loss can increase the risk of gallstones, which should be taken into consideration. It may also affect blood coagulation; therefore, patients on oral anticoagulants must regularly monitor coagulation parameters. This medication may interact with some drugs, so patients taking immunosuppressants, antiepileptics, antiretrovirals, or anticoagulants should consult their physician before use and monitor drug concentrations or effects. It is safer not to use this medication during pregnancy or breastfeeding, and it is not recommended for children under 12 years old. In case of overdose, 24-hour observation is needed, and generally, the effects of the drug recover quickly. This medication should be stored out of reach of children and kept in its original packaging to protect it from light and moisture.

• fatty stools
• abdominal bloating and gas
• frequency of stools
• fatty/frothy stools
• fatty bowel movements
• increased bowel movements
• fecal incontinence
• abdominal pain/discomfort
• nausea
• infectious diarrhea

This medication should be stored in a tightly closed container to protect it from air, light, and moisture. It is important to store it at a cool temperature below 25 degrees Celsius to maintain the medication's effectiveness.

Appearance

Hard capsules with a white or off-white powder or granules, and yellow-colored upper and lower parts.

Package unit

90 capsules/PTP [90 capsules (10 capsules/PTPX9)], 300 capsules/bottle [300 capsules/bottle]