Nobask Tablet 2.5 mg (Amlodipine Besylate)

Adult dose

Administer 5 mg orally once a day as amlodipine, which may be increased to a maximum of 10 mg per day depending on the patient's response. Adjustments should be made based on age and symptoms.

Child dose

The effective oral dose of amlodipine for blood pressure reduction is 2.5 mg-5 mg once a day. Doses exceeding 5 mg per day have not been studied in pediatric patients.

This drug should not be used in certain patients. For example, people allergic to this drug or similar drug classes, nursing mothers, patients with severe liver dysfunction, patients with severe aortic stenosis, and patients in shock should not take this drug. Additionally, patients with severe hypotension, nephropathy requiring dialysis, the elderly, and women who are pregnant or may become pregnant should use this drug with extreme caution. Use during pregnancy is only recommended in special cases, and nursing mothers should discontinue breastfeeding while taking this drug. While taking this drug, various side effects may occur. Common side effects include flushing, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Rarely, side effects like excessive lowering of blood pressure, vasculitis, neurological symptoms, erectile dysfunction, gynecomastia, dyspepsia, weight changes, skin rashes, and liver dysfunction may occur. Patients with heart failure should be cautious as symptoms of pulmonary congestion may worsen with this drug, and dose adjustment is necessary for patients with impaired liver function. Furthermore, this drug's effects appear slowly, so it is not suitable for acute angina treatment. This drug can interact with several other medications. Particularly, combining it with grapefruit juice may excessively increase the blood pressure-lowering effect, so they should not be taken together. Caution is also needed when used in combination with certain antibiotics, antihypertensives, diuretics, and immunosuppressants, and consultation with a doctor or pharmacist is advisable. In case of overdose, blood pressure may fall severely and heart rhythms may become irregular, so immediate medical attention is required, and emergency measures such as gastric lavage or activated charcoal administration may be necessary. Finally, this drug can be used in children and the elderly, but safety and efficacy have not been established for children under 6 years of age. For the elderly, a standard dose should be used while carefully monitoring for any side effects.

Serious side effects

Urticaria, severe swelling (edema), angioedema, severe allergic reactions, toxic epidermal necrolysis, severe skin abnormal reactions, dyspnea, breathing problems, jaundice, liver abnormalities, myocardial infarction, arrhythmias, chest pain, serious heart-related symptoms, significantly reduced urine output, generalized severe edema and increased blood pressure.

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This drug is sensitive to light, so it should be stored in a special container that does not allow light to enter. Additionally, it is recommended to store it at room temperature between 15°C and 30°C. Proper storage can maintain the drug's efficacy and safety.

Appearance

Flat diamond-shaped white tablets

Package unit

Bottle - 30 tablets/bottle