Darim Celecoxib Capsule 200 mg

Adult dose

The minimum recommended dose of this drug should be adjusted for each patient. It may be taken with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks at 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a doctor or pharmacist if the person regularly consumes more than three drinks daily, as there is a risk of gastrointestinal bleeding. It may increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke, so it should be used at the lowest effective dose for the shortest duration possible, and any cardiovascular symptoms that arise should be discussed immediately with medical personnel. There is a risk of severe gastrointestinal issues such as perforation, ulcers, or bleeding, especially in elderly patients or those with a history of gastrointestinal disease. Careful observation is necessary, and any gastrointestinal symptoms should be treated immediately. Patients with hypersensitivity to this medication or a specific history of allergies, severe liver or kidney impairment, active peptic ulcer disease, etc., should not take this medication. Patients with specific conditions such as liver impairment, kidney impairment, asthma, heart failure, hypertension, edema, or the elderly should use this medication carefully and regularly monitor their condition under medical guidance. This medication can cause various adverse reactions, including dyspepsia, headache, dizziness, skin rash, hypertension, edema, etc. If symptoms are severe or persist, consultation with a doctor is necessary. This medication may affect liver and kidney functions, necessitating regular blood tests and liver and kidney function tests. If any abnormal signs are found, administration should be stopped immediately. Pregnant women, those who might become pregnant, and nursing mothers should not take this medication, and women planning to conceive should be cautious as it may affect fertility. The safety and effectiveness of this medication in children and adolescents have not been established, so it should not be administered to individuals under 18 years of age. This medication may interact with other drugs, so patients should inform their healthcare provider of any concurrent medications and take care especially when used with drugs metabolized in the liver. Dizziness or drowsiness may occur while taking this medication, so driving or operating machinery should be avoided. In case of overdose, symptoms such as lethargy, vomiting, gastrointestinal bleeding, and acute renal failure may occur. Therefore, do not exceed the recommended dose and contact medical personnel immediately if any abnormal symptoms appear. Keep this medication out of reach of children, do not transfer it to another container, and pay attention to quality maintenance during storage.

Gastrointestinal bleeding, cardiovascular thrombotic reaction, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confused state, dizziness, muscular hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, bowel perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, injury, headache, leg cramps, tension hyperactivity, sensory decline, migraine, neuralgia, neuropathy, sensory distortion, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, ageusia, back pain, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, insomnia, decreased appetite, increased appetite, depression, neuro irritability, drowsiness, fatal intracranial hemorrhage, hallucination, worsening of epilepsy, upper respiratory tract infection, sinusitis, pharyngitis, rhinitis, bronchospasm, exacerbated bronchospasm, dyspnea, laryngitis, pneumonia, nosebleed, voice disorders, vesicular dermatitis, dermatitis, nail disease, photosensitive reaction, pruritus, erythematous rash, macular papular rash, skin disease, skin dryness, increased sweating, erythema multiforme, exfoliative dermatitis, skin and mucous membrane syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash accompanied by eosinophilia and systemic symptoms, arrhythmia, left ventricular hypertrophy, angina, unstable angina, coronary artery disease, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral necrosis, thrombophlebitis, vasculitis, deep vein thrombosis, cerebral hemorrhage, isolation, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic disease of the breast, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, decreased appetite, increased LDH, hypoglycemia, hyponatremia, synovial cyst, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, fracture, tendon rupture, pain in various body parts, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopathy, anemia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic esophagitis, contact dermatitis, injection site reaction, dermal nodules, altered taste, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, blurring of vision, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reaction, hallucination, cerebral hemorrhage, loss of taste, loss of smell, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, photosensitive reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, micro-patch glomerulonephritis, menstrual disorders, female infertility, chest pain, lethargy, drowsiness, nausea, upper abdominal pain, hypertension, acute renal failure, respiratory depression, coma

This medication should be stored in a tightly closed container to prevent air and moisture ingress, and it is important to maintain the storage temperature between 15 and 30 degrees Celsius. This way, the effectiveness of the medication can be safely preserved.

Appearance

White to pale yellow powder filled in white capsules with yellow bands on both ends

Package unit

30 Capsules/Bottle, 100 Capsules/Bottle