Esomeprazole Magnesium Hydrate 40 mg

Adult dosage

This medication should be swallowed with liquids such as water and must not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. If symptoms persist, an additional 4 weeks is required. - Maintenance therapy for prevention of recurrence: 20 mg once daily. - Treatment of symptoms without esophagitis: 20 mg once daily. If symptoms persist after 4 weeks, further medical advice is necessary.

Children's dosage

Adolescents over 12 years - Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. If symptoms persist, additional 4 weeks of medication is required. - For gastroesophageal reflux disease without esophagitis:

This medication should not be used in certain patients. For example, patients who are allergic or have had adverse reactions to this medication or its ingredients, or to benzimidazole derivatives, should not take it. Additionally, patients with hypersensitivity to penicillin antibiotics or macrolide antibiotics should not take this medication when combined with those antibiotics for the eradication of Helicobacter pylori. Patients or nursing mothers taking certain medications, such as terfenadine, cisapride, pimodidine, astemizole, atazanavir, nelfinavir, or rilpivirine, should avoid using this medication. This medication can cause various side effects, which may include blood-related problems such as leukopenia, thrombocytopenia, and agranulocytosis, which are rare. Immunologically, symptoms like fever, angioedema, and severe allergic reactions may occur. In metabolic and nutritional aspects, edema, hyponatremia, and hypomagnesemia have been reported; hypomagnesemia could also affect calcium and potassium levels. Mental health issues such as insomnia, anxiety, confusion, depression, and rarely aggression or hallucinations may arise. Common neurological side effects include headaches, dizziness, and drowsiness. Gastrointestinal issues may include abdominal pain, constipation, diarrhea, nausea, and vomiting, with rare reports of pancreatitis or gastroenteritis. Liver function abnormalities or jaundice can occur, and liver failure may rarely happen, necessitating caution regarding liver health. Dermatological reactions may include rashes, itching, hair loss, and severe skin reactions such as Stevens-Johnson syndrome in severe cases. Musculoskeletal issues like fractures, arthralgia, myalgia have also been reported. Long-term use of this medication requires regular checks for abnormalities. It can suppress gastric acid secretion, possibly promoting bacterial growth in the stomach and slightly increasing infection risk. This is particularly important in hospitalized patients, who may have a higher risk of diarrhea caused by Clostridium difficile. Furthermore, this medication may increase the risk of osteoporotic fractures, so patients at risk of fractures require proper monitoring. This medication can interact with certain drugs, so it is essential to consult with a doctor or pharmacist if other medications are being taken. The safety of this medication during pregnancy has not been fully established, so caution is advised; it is also best not to take it during breastfeeding. In case of overdose, there are no specific antidotes; appropriate treatment should be provided based on symptoms. It should be stored out of reach of children.

Serious side effects

Urticaria, angioedema, anaphylactic reaction, shock, hypomagnesemia, severe hypomagnesemia, jaundice, liver failure, encephalopathy, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, eosinophilia and systemic symptom drug reaction (DRESS syndrome), interstitial nephritis, rhabdomyolysis, severe allergic reactions, severe skin reactions, severe

Mild side effects

Headache, dizziness, abnormal sensations, drowsiness, taste disturbances, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal distension, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, increased liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, muscle weakness, fatigue, increased sweating, Clostridium difficile associated diarrhea, abdominal distension, allergic reactions, back pain, chest pain, retrosternal pain,

Store this medication in a tightly sealed container to protect it from air and moisture; the ideal storage temperature is room temperature between 1°C and 30°C. Storing it this way helps maintain the efficacy of the medication for a longer period.

Appearance

Pink round film-coated tablets

Package unit

28 tablets (14 tablets/AluAlu x 2)