Omexil Tablet 20 mg (Olmesartan Medoxomil)

Adult dose

The recommended initial dose is 10mg once daily, taken regardless of meals. If blood pressure is not adequately controlled at this dose, it may be increased to 20mg once daily, and if necessary, up to a maximum of 40mg once daily. The antihypertensive effect appears within two weeks after treatment initiation, with the maximum effect occurring around eight weeks. If blood pressure is not adequately controlled with monotherapy, thiazide diuretics can be co-administered.

Child dose

Safety and efficacy in pediatric patients have not been established.

This drug can cause serious harm to the fetus and newborn when taken during the second and third trimesters of pregnancy, so it should be discontinued immediately if pregnancy is confirmed. Individuals with allergies to the ingredients in this drug, pregnant women, nursing mothers, patients on renal dialysis, patients with severe liver dysfunction, patients with biliary obstruction, and those with specific genetic lactose intolerance should not take this medication. Caution is required when administering this drug to patients who are dehydrated or have low blood volume or sodium, as hypotension may occur. Patients with weakened kidney function or those who have undergone kidney transplantation should also have regular kidney function tests. Additionally, this drug should be used cautiously in patients with narrowed renal arteries, those at risk of hyperkalemia, or those with issues related to the aorta or heart valves, as there is a risk of low blood pressure causing dizziness, necessitating care during hazardous tasks. While taking this medication, side effects such as dizziness, headache, abdominal pain, nausea, muscle pain, and skin rash may occur, although most are mild and temporary. If chronic diarrhea or weight loss occurs, discontinuation of this drug and consultation with a physician is advised. Symptoms like abdominal pain or vomiting should also be monitored due to the possibility of intestinal vascular edema. When taken with other antihypertensive medications, potassium-sparing diuretics, or potassium supplements, blood potassium levels may rise, so blood tests should be conducted to monitor the condition. Patients taking lithium should avoid using this medication concurrently, and caution should be exercised when used with non-steroidal anti-inflammatory drugs, as renal function may worsen. Pregnant women must avoid this medication due to the potential for serious side effects to the fetus and newborn. Nursing mothers should either discontinue breastfeeding or stop taking this medication to prevent effects on the infant. Its safety and efficacy in children have not been established, so it is not recommended for use in this population. Elderly patients may experience higher concentrations of this drug in the body, so caution is necessary during administration. In cases of overdose, symptoms such as hypotension, palpitations, and bradycardia may appear; patients should inform medical personnel immediately for appropriate treatment.

Serious side effects

Urticaria, severe swelling (including angioedema, facial edema, and peripheral edema), chest pain, difficulty breathing (including asthma), severe allergic reactions (anaphylaxis), severe skin adverse reactions (severe rash, blisters, skin peeling, mucosal pain), liver abnormalities (abnormal liver function tests, potential jaundice), acute renal failure, elevated serum creatinine, severe edema, severe headache, seizures, altered consciousness, visual disturbances, paralysis,

Mild side effects

• Dizziness
• headache
• palpitations
• hypercholesterolemia
• hyperlipidemia
• hyperuricemia
• arthralgia
• arthritis
• muscle pain
• abdominal pain

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is also best kept at room temperature, ideally between 1 to 25 degrees Celsius, avoiding extremes of heat or cold.

Appearance

White, round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle