Omexil Tablet 40mg (Olmesartan Medoxomil)

Adult dose

The recommended initial dose is 10mg once daily, irrespective of meals. If blood pressure is not adequately controlled at this dose, it may be increased to 20mg once daily. If further blood pressure-lowering effect is needed, it may be increased to a maximum of 40mg once daily. The blood pressure-lowering effect appears within 2 weeks of starting treatment, with maximum effect observed after about 8 weeks. If blood pressure is not adequately controlled with monotherapy, it can be combined with thiazide diuretics such as hydrochlorothiazide.

Child dose

The safety and efficacy in pediatric patients have not been established.

This medication can cause serious harm or death to the fetus and newborn if taken during the second or third trimester of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. Individuals allergic to any component of this medication, pregnant or breastfeeding women, patients on renal dialysis, patients with severe liver disease, patients with biliary obstruction, and certain genetically lactose intolerant patients should not take this medication. Patients with decreased blood volume or sodium may experience low blood pressure; therefore, the condition should be well assessed before starting treatment, and if symptoms of low blood pressure occur, appropriate measures should be taken immediately. Patients with impaired renal function, kidney transplant recipients, patients with renovascular hypertension, and patients at risk of hyperkalemia should also use this medication cautiously and should regularly check renal function and electrolyte status through blood tests. Patients with aortic or mitral valve stenosis, obstruction, and hypertrophic cardiomyopathy should take this medication with special caution. This medication may cause side effects such as dizziness, so it is advisable to avoid hazardous activities such as working at heights or driving. Although it is generally safe to use, various side effects can occur, such as dizziness, headache, gastrointestinal discomfort, hyperkalemia, blood pressure changes, etc., and any unusual symptoms should be consulted with a healthcare professional. When taken with other antihypertensive agents or potassium-sparing diuretics, or potassium supplements, there may be an increase in serum potassium levels, so caution is required when used in combination. Taking with lithium preparations may increase lithium levels and lead to toxicity, therefore concurrent use of this medication and lithium is not recommended. Caution is needed when used in combination with nonsteroidal anti-inflammatory drugs due to the risk of renal function impairment; regular hydration and renal function checks are necessary during the course of treatment. This medication is not administered to pregnant women due to the severe risk of fetal harm and alternative treatments should be considered during pregnancy. Breastfeeding women should discontinue nursing or stop taking this medication as it may pass into breast milk and cause adverse reactions in infants. Safety and efficacy in pediatric patients have not yet been established, so it should be used cautiously in children. Elderly patients may experience higher body levels of this medication, hence dose adjustment and caution are necessary. Overdose may indicate symptoms such as low blood pressure and palpitations; if these symptoms occur, immediate treatment from medical professionals is necessary. This medication has been reported to have a low risk of carcinogenic or genotoxic effects even after prolonged use; however, it is crucial to discuss with healthcare professionals before and after administration.

Serious side effects

Urticaria, severe swelling (edema), angioedema, anaphylactic reaction, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, difficulty breathing or dyspnea, asthma attacks, respiratory issues accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme lethargy, acute renal failure, increased serum creatinine, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances

Mild side effects

Dizziness, headache, palpitations, hypercholesterolemia, hyperlipidemia, hyperuricemia, arthralgia, arthritis, myalgia, rash, vomiting, similar gastrointestinal disorders to chronic malabsorption, rhabdomyolysis, hair loss, itching, increase in blood pressure, elevated serum creatinine, back pain, abdominal pain, diarrhea, chest pain, cough, epistaxis, upper respiratory infection, asthma, angioedema, facial edema, peripheral edema, increased serum bilirubin levels, elevated liver enzyme levels

This medicine should be stored in a tightly sealed container to prevent exposure to air or moisture. It is advisable to keep it at room temperature between 1 and 25 degrees Celsius.

Appearance

White oblong film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle