Cerwin Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Administer 200 mg of celecoxib once daily, or 100 mg per dose in 2 divided doses daily. 2. Rheumatoid arthritis: Administer 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg per dose in 2 divided doses daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment at 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This drug should be discussed with a doctor or pharmacist if the patient consumes alcohol heavily daily, as it increases the risk of gastrointestinal bleeding. This drug may increase the risk of cardiovascular thrombotic events such as heart attack and stroke, so it should only be used at the minimum effective dose for the shortest possible duration. There is a risk of developing ulcers or bleeding in the gastrointestinal tract, so special monitoring is required for the elderly and those with a history of gastrointestinal diseases. This drug should not be administered to patients with certain allergies, severe liver or kidney dysfunction, women who are pregnant or breastfeeding, or patients with cardiovascular diseases. Patients with liver or kidney problems or a history of hypertension, heart failure, asthma, etc., should use this drug cautiously and require regular check-ups. Dizziness or drowsiness may occur during treatment, so it is advisable to avoid driving or operating machinery. This drug may interact with other medications, so it is essential to consult healthcare providers if taking other medicines. Women who are pregnant or planning to become pregnant should avoid this medication, and if pregnancy is confirmed while taking it, treatment should be discontinued immediately. Women taking this drug for a long time need to be cautious due to the possibility of temporary infertility. Regular blood tests and liver and kidney function assessments are important to detect signs of abnormalities early. In case of overdose, symptoms such as vomiting, drowsiness, and abdominal pain may occur, and appropriate medical treatment should be sought immediately. Keep out of reach of children and do not transfer to another container to maintain the drug's safety and quality.

Gastrointestinal bleeding, cardiovascular thromboembolic events, myocardial infarction, stroke, perforation of upper and lower gastrointestinal tracts, ulcer, hemorrhage, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, pruritus, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, frequency of urination, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbances, cataract, conjunctivitis, ocular pain, glaucoma, intraocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary occult blood, positive urinary protein, renal impairment, acute renal failure, interstitial nephritis, headache, leg cramps, hypertension, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, back pain, exacerbation of allergies, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, angioedema, loss of appetite, increased appetite, depression, neuroexcitation, drowsiness, fatal intracranial hemorrhage, hallucinations, worsening of epilepsy, upper respiratory tract infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, chest neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cyst, hearing loss, ear abnormalities, ear pain, deafness, hepatic dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urinary urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, elevated alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, synovial bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical syndrome, synovitis, tendinitis, myositis, fracture, tendon rupture, pain in various parts of the body, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, pansinusitis, contact dermatitis, injection site reactions, skin nodules, visual disturbances, cataract, conjunctivitis, ocular pain, glaucoma, intraocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary occult blood, positive urinary protein, renal impairment, acute renal failure, interstitial nephritis, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, ageusia, anosmia, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, menstrual disorders, chest pain, lethargy, drowsiness, nausea, vomiting, upper abdominal pain, hypertension, acute renal failure, respiratory depression, coma

This drug should be stored in a sealed container to prevent air from entering, and it is advisable to keep it at room temperature between 15 and 30 degrees Celsius. Storing it this way will help maintain its effectiveness.

Appearance

A white capsule filled with white to light yellow powder with a yellow line on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle