Selenumin Injection (Selenium Acid)

Adult dosage

Adult: In stable metabolic total parenteral nutrition (TPN), administer 20 to 40 μg of selenium (this drug contains 40 μg/mL of selenium) per day.

Children's dosage

Pediatric: Administer 3 μg per day per kg of body weight. Plasma selenium concentrations should be monitored frequently for reference during the next dosing.

This drug contains selenium and should not be used in patients with selenium toxicity. Toxicity may occur with an overdose, and use should be stopped immediately if adverse symptoms appear. This drug should be diluted before administration to avoid phlebitis, as it should not be administered directly into the peripheral vein without dilution. Additionally, since it is a storage solution, it must be mixed before administration. Care should be taken when administering this drug to patients with impaired kidney function or premature infants, as aluminum toxicity may occur with long-term parenteral administration due to aluminum content. Pain or allergic reactions may occur during administration, though rarely; in such cases, use should be discontinued, and a specialist consulted. Symptoms such as dermatitis, foul odor during sweating or breathing, hair loss, restlessness, and vomiting should result in immediate cessation of use and consultation with a doctor or pharmacist. Before administration, visually check for any precipitate or discoloration, and prepare under aseptic conditions. If kidney or digestive function is poor, selenium dosage may need to be adjusted. In blood transfusion patients, selenium dosage should be considered, and blood concentration should be continuously monitored. This drug should only be used in pregnant women or women of childbearing potential if the therapeutic benefits outweigh the risks to the fetus. Its safety has not been established in nursing mothers, so it is advisable to either stop breastfeeding or discontinue administration. In case of overdose, chronic symptoms such as dermatitis, vomiting, and hair loss may occur, and in severe cases, life-threatening symptoms such as vascular collapse and pulmonary hemorrhage may develop. In cases of overdose, gastric lavage, induction of diuresis, or vitamin C administration may be necessary, and in extreme cases, dialysis may be required to remove selenium. This drug should be kept out of reach of children and should be used immediately after opening; transferring to another container should be avoided. In adults receiving long-term nutritional injections, selenium deficiency can be improved by administering this drug for a certain period.

Serious side effects

Allergic reactions (possibility of hives, severe swelling)

Mild side effects

• Pain
• dermatitis
• foul odor during sweating or breathing
• hair loss
• restlessness
• vomiting

This drug should be stored in a tightly sealed container to prevent exposure to air and moisture. It is advisable to maintain a storage temperature between 15 degrees and 30 degrees Celsius.

Appearance

A colorless and odorless transparent liquid contained in a colorless transparent vial injection.

Package unit

10 vials/box [(20 mL/vial x 10 vials)]